Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle.
about
Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptorContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisChaperone machines for protein folding, unfolding and disaggregationThe dynamic conformational cycle of the group I chaperonin C-termini revealed via molecular dynamics simulationDe novo modeling of the F 420 -reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopyThe molecular architecture of the eukaryotic chaperonin TRiC/CCTVisualizing GroEL/ES in the Act of Encapsulating a Folding ProteinThe structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCTAssisted protein folding at low temperature: evolutionary adaptation of the Antarctic fish chaperonin CCT and its client proteinsxTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometryHigh resolution single particle refinement in EMAN2.1.Multiscale natural moves refine macromolecules using single-particle electron microscopy projection imagesSingle particle tomography in EMAN2Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO.Ring Separation Highlights the Protein-Folding Mechanism Used by the Phage EL-Encoded Chaperonin.Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers.TRiC's tricks inhibit huntingtin aggregation.Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions.ATP-driven molecular chaperone machines.The Mechanism and Function of Group II Chaperonins.Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components.Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacteriumAn information theoretic framework reveals a tunable allosteric network in group II chaperonins.Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer.Identification of an allosteric network that influences assembly and function of group II chaperonins.Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT.Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog.
P2860
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P2860
Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Symmetry-free cryo-EM structur ...... se-driven conformational cycle
@nl
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@ast
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@en
type
label
Symmetry-free cryo-EM structur ...... se-driven conformational cycle
@nl
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@ast
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@en
prefLabel
Symmetry-free cryo-EM structur ...... se-driven conformational cycle
@nl
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@ast
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Symmetry-free cryo-EM structur ...... e-driven conformational cycle.
@en
P2093
Joanita Jakana
Matthew T Dougherty
Michael F Schmid
Stefanie Reissmann
Steven L Ludtke
P2860
P304
P3181
P356
10.1038/EMBOJ.2011.366
P407
P577
2011-11-01T00:00:00Z