Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease
about
Update on pathogenesis and treatment of CLEAicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletionThe Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.Human DNA Exonuclease TREX1 Is Also an Exoribonuclease That Acts on Single-stranded RNA.Human disease phenotypes associated with mutations in TREX1.A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1.Autoimmunity: Why the Body Attacks Itself
P2860
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P2860
Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease
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2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Defects in DNA degradation rev ...... s linked to autoimmune disease
@ast
Defects in DNA degradation rev ...... s linked to autoimmune disease
@en
Defects in DNA degradation rev ...... s linked to autoimmune disease
@nl
type
label
Defects in DNA degradation rev ...... s linked to autoimmune disease
@ast
Defects in DNA degradation rev ...... s linked to autoimmune disease
@en
Defects in DNA degradation rev ...... s linked to autoimmune disease
@nl
prefLabel
Defects in DNA degradation rev ...... s linked to autoimmune disease
@ast
Defects in DNA degradation rev ...... s linked to autoimmune disease
@en
Defects in DNA degradation rev ...... s linked to autoimmune disease
@nl
P2093
P2860
P1433
P1476
Defects in DNA degradation rev ...... s linked to autoimmune disease
@en
P2093
Fred W Perrino
Scott Harvey
Suzanna L Bailey
Thomas Hollis
P2860
P356
10.1016/J.DNAREP.2011.10.007
P577
2012-01-02T00:00:00Z