Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents
about
Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of TuberculosisFragment-Based Discovery of 6-Azaindazoles As Inhibitors of Bacterial DNA LigaseTricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agentsRecent contributions of structure-based drug design to the development of antibacterial compounds.A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteriaRepurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus.Discovery of ATP-Competitive Inhibitors of tRNAIle Lysidine Synthetase (TilS) by High-Throughput Screening.Biological evaluation and molecular modelling study of thiosemicarbazide derivatives as bacterial type IIA topoisomerases inhibitors.Hot-spot identification on a broad class of proteins and RNA suggest unifying principles of molecular recognition.Thermodynamic computational approach to capture molecular recognition in the binding of different inhibitors to the DNA gyrase B subunit from Escherichia coli.Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.Assays, surrogates, and alternative technologies for a TB lead identification program targeting DNA gyrase ATPase.
P2860
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P2860
Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@ast
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en-gb
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
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type
label
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@ast
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en-gb
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@nl
prefLabel
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@ast
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en-gb
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@nl
P2093
P2860
P356
P1476
Pyrrolamide DNA Gyrase Inhibit ...... Identify Antibacterial Agents
@en
P2093
Alok Singh
Ann E Eakin
April Blodgett
Beth Andrews
Brian Sherer
Bryan Prince
Dave Timms
George Mullen
Grant K Walkup
Haihong Ni
P2860
P304
P356
10.1128/AAC.05485-11
P407
P50
P577
2012-03-01T00:00:00Z