Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4 - Wikidata - awgldk - TriplyDB

Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

http://www.wikidata.org/entity/Q27678108

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Sulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognition Structural Model of the Extracellular Assembly of the TCR-CD3 Complex.Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection Reconciling views on T cell receptor germline bias for MHC Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3 T cell receptor bias for MHC: co-evolution or co-receptors?The immune synapse clears and excludes molecules above a size threshold.Size-based chromatography of signaling clusters in a living cell membrane The immunology connection--my first T cell receptor structure projects.Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function Piecing together the family portrait of TCR-CD3 complexes.Molecular architecture of the αβ T cell receptor-CD3 complex.Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization Pre-TCR ligand binding impacts thymocyte development before αβTCR expression.Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR.Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.The T-cell receptor is not hardwired to engage MHC ligands.Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity.Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Recognition of self and altered self by T cells in autoimmunity and allergy.The molecular determinants of CD8 co-receptor function.Structural basis for self-recognition by autoimmune T-cell receptors.The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset Commitment The T cell antigen receptor: the Swiss army knife of the immune system.Codification of bidentate pMHC interaction with TCR and its co-receptor.A flexible docking approach for prediction of T cell receptor-peptide-MHC complexes.The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR-CD3-pMHC-CD4 Macrocomplex.TCR Signaling Emerges from the Sum of Many Parts Revisiting the putative TCR Cα dimerization model through structural analysis.Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination.Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex.Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma.Dimensions and Interactions of Large T-Cell Surface Proteins Hydrodynamic trapping measures the interaction between membrane-associated molecules

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

http://www.wikidata.org/entity/Q27678108

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Proceedings of the National Academy of Sciences of the United States of America

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Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

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Roy A Mariuzza

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Xin Xiang Wang

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Yiyuan Yin

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P2860

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

CD4 dimers constitute the functional component required for T cell activation

Dimeric association and segmental variability in the structure of human CD4

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

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22431638

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crystal structure

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3325661

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