Conversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING - Wikidata - awgldk - TriplyDB

Conversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING

Conversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING

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Rate of steroid double-bond reduction catalysed by the human steroid 5β-reductase (AKR1D1) is sensitive to steroid structure: implications for steroid metabolism and bile acid synthesis 5β-Reduced steroids and human Δ(4)-3-ketosteroid 5β-reductase (AKR1D1).Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry.Boosting the Catalytic Performance of Metal-Organic Frameworks for Steroid Transformations by Confinement within a Mesoporous Scaffold.Identification and functional characterization of four novel aldo/keto reductases in Anabaena sp. PCC 7120 by integrating wet lab with in silico approaches.

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Conversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING

http://www.wikidata.org/entity/Q27678144

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2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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Conversion of Human Steroid 5 ...... OF PERFECT ENZYME ENGINEERING

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JBC.M111.338780

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Journal of Biological Chemistry

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Conversion of human steroid 5β ...... of perfect enzyme engineering

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David W Christianson

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Jason E Drury

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Mo Chen

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P2860

Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

PROCHECK: a program to check the stereochemical quality of protein structures

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization

Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution

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16609-16622

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scholarly article

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10.1074/JBC.M111.338780

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20

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287

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Trevor M Penning

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22437839

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3351325

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