A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen - Wikidata - awgldk - TriplyDB

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

http://www.wikidata.org/entity/Q27678481

about

E2 enzymes: more than just middle men KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Crystal Structure of a Ube2S-Ubiquitin Conjugate A pathogen type III effector with a novel E3 ubiquitin ligase architecture.Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer Intrinsic disorder drives N-terminal ubiquitination by Ube2w UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.Genome-Wide Identification, Phylogenetic and Expression Analyses of the Ubiquitin-Conjugating Enzyme Gene Family in Maize System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.Biochemical and structural characterization of a novel ubiquitin-conjugating enzyme E2 from Agrocybe aegeria reveals Ube2w family-specific properties Characterization and expression analysis of genes encoding ubiquitin conjugating domain-containing enzymes in Carica papaya.Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34 UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119.Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled.Activity-Based Probes for HECT E3 Ubiquitin Ligases Evaluation of Reference Genes for Quantitative Real-Time PCR Analysis of the Gene Expression in Laticifers on the Basis of Latex Flow in Rubber Tree (Hevea brasiliensis Muell. Arg.).Modeling oblong proteins and water-mediated interfaces with RosettaDock in CAPRI rounds 28-35.Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery The use of ubiquitin lysine mutants to characterize E2-E3 linkage specificity: Mass spectrometry offers a cautionary "tail".EBV-Associated Cancer and Autoimmunity: Searching for Therapies.Core Mediator structure at 3.4 Å extends model of transcription initiation complex.Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.Involvement of Parkin in the ubiquitin proteasome system-mediated degradation of N-type voltage-gated Ca2+ channels.Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme.Protein-protein interactions in paralogues: Electrostatics modulates specificity on a conserved steric scaffold.Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers.Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.A muscle-specific MuRF1-E2 network requires stabilization of MuRF1-E2 complexes by telethonin, a newly identified substrate.Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors.An E2-guided E3 Screen Identifies the RNF17-UBE2U Pair as Regulator of the Radiosensitivity, Immunodeficiency, Dysmorphic Features, and Learning Difficulties (RIDDLE) Syndrome Protein RNF168.Performance of ZDOCK and IRAD in CAPRI rounds 28-34.

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P2860

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

http://www.wikidata.org/entity/Q27678481

description

2012 nî lūn-bûn

@nan

2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@ast

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@en

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@nl

type

label

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@ast

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@en

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@nl

prefLabel

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@ast

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@en

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

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MCP.O111.013706

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Molecular & Cellular Proteomics

P1476

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

@en

P2093

Brian Raught

http://www.w3.org/2001/XMLSchema#string

Dante Neculai

http://www.w3.org/2001/XMLSchema#string

George V Avvakumov

http://www.w3.org/2001/XMLSchema#string

Janet W Wan

http://www.w3.org/2001/XMLSchema#string

Jenny H Hong

http://www.w3.org/2001/XMLSchema#string

John R Walker

http://www.w3.org/2001/XMLSchema#string

Jonathan Shloush

http://www.w3.org/2001/XMLSchema#string

Ryan Doherty

http://www.w3.org/2001/XMLSchema#string

Sheng Xue

http://www.w3.org/2001/XMLSchema#string

Sung K Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

The Protein Data Bank

Recognition of the polyubiquitin proteolytic signal

Electrostatics of nanosystems: application to microtubules and the ribosome

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329-41

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scholarly article

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3215064

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10.1074/MCP.O111.013706

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8

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11

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Sirano Dhe-Paganon

Cheryl Arrowsmith

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2012-08-01T00:00:00Z

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22496338

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3412965

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