Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

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http://www.wikidata.org/entity/Q27679142
The linker connecting the two kringles plays a key role in prothrombin activationAtomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion holeChanges in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS.Improved hemostasis in hemophilia mice by means of an engineered factor Va mutantStructural insights into the interaction of blood coagulation co-factor VIIIa with factor IXa: a computational protein-protein docking and molecular dynamics refinement study.Phosphatidylserine and FVa regulate FXa structure.Prothrombin structure: unanticipated features and opportunities.How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of ProthrombinAtomic-level description of protein-lipid interactions using an accelerated membrane model.The Fragment 1 Region of Prothrombin Facilitates the Favored Binding of Fragment 12 to Zymogen and Enforces Zymogen-like Character in the Proteinase.Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation.Novel insights into the regulation of coagulation by factor V isoforms, tissue factor pathway inhibitorα, and protein S.The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin.Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors.Membrane Interaction of the Factor VIIIa Discoidin Domains in Atomistic Detail.Minor Plasma Lipids Modulate Clotting Factor Activities and May Affect Thrombosis Risk.Structure of Coagulation Factor II: Molecular Mechanism of Thrombin Generation and Development of Next-Generation Anticoagulants
P2860

Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

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http://www.wikidata.org/entity/Q27679142
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2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@ast
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@en
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@nl
type
label
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@ast
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@en
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@nl
prefLabel
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@ast
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@en
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis
@en
P2093
P2860
P304
P31
P356
10.1182/BLOOD-2013-06-511733
P407
P433
P478
P50
P577
P5875
P698
P921
P932