Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA
about
Prohead RNA: a noncoding viral RNA of novel structure and functionDiscovery of a new motion mechanism of biomotors similar to the earth revolving around the sun without rotation.Mechanism of one-way traffic of hexameric phi29 DNA packaging motor with four electropositive relaying layers facilitating antiparallel revolution.The ATPase of the phi29 DNA packaging motor is a member of the hexameric AAA+ superfamily.Revolution rather than rotation of AAA+ hexameric phi29 nanomotor for viral dsDNA packaging without coiling.Directional mechanical stability of Bacteriophage φ29 motor's 3WJ-pRNA: Extraordinary robustness along portal axisCommon mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotationEnhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles.Binomial distribution for quantification of protein subunits in biological nanoassemblies and functional nanomachinesRegression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying both Ligand and siRNA.Triptycene-based small molecules modulate (CAG)·(CTG) repeat junctions.Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration.RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applicationsSystemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology.New approach to develop ultra-high inhibitory drug using the power function of the stoichiometry of the targeted nanomachine or biocomplex.Biological Nanomotors with a Revolution, Linear, or Rotation Motion MechanismThree-way junction conformation dictates self-association of phage packaging RNAsDevelopment of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors with Revolving Mechanism.Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor.Stable RNA nanoparticles as potential new generation drugs for cancer therapy.Thermodynamic stabilities of three-way junction nanomotifs in prohead RNA.Insights into the structure and assembly of the bacteriophage 29 double-stranded DNA packaging motorSingle molecule photobleaching (SMPB) technology for counting of RNA, DNA, protein and other molecules in nanoparticles and biological complexes by TIRF instrumentation.Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotorsControllable self-assembly of RNA dendrimersRNA as a boiling-resistant anionic polymer material to build robust structures with defined shape and stoichiometry.Entropy-driven one-step formation of Phi29 pRNA 3WJ from three RNA fragments.Engineering Structurally Interacting RNA (sxRNA).A Fluorescent Split Aptamer for Visualizing RNA-RNA Assembly In VivoFinding of widespread viral and bacterial revolution dsDNA translocation motors distinct from rotation motors by channel chirality and sizeIn-gel imaging of RNA processing using broccoli reveals optimal aptamer expression strategies.Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting.Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs.Dual Tumor-Targeting Nanocarrier System for siRNA Delivery Based on pRNA and Modified Chitosan.Diverse self-association properties within a family of phage packaging RNAs.Physicochemically tunable polyfunctionalized RNA square architecture with fluorogenic and ribozymatic properties.RNA Nanoparticle-Based Targeted Therapy for Glioblastoma through Inhibition of Oncogenic miR-21.Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles.Using Planar Phi29 pRNA Three-Way Junction to Control Size and Shape of RNA Nanoparticles for Biodistribution Profiling in Mice.Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2'-F RNA, and LNA in the context of Phi29 pRNA 3WJ.
P2860
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P2860
Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@ast
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@en
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@nl
type
label
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@ast
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@en
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@nl
prefLabel
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@ast
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@en
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of 3WJ core ...... the Phi29 hexameric motor pRNA
@en
P2093
Farzin Haque
James A Endrizzi
Lyudmila S Shlyakhtenko
Peixuan Guo
Young-In Chi
Yuri Lyubchenko
P2860
P304
P356
10.1261/RNA.037077.112
P407
P577
2013-09-01T00:00:00Z