Factors influencing the specificity of inhibitor binding to the human and malaria parasite dihydroorotate dehydrogenases
about
Recent advances in malaria drug discoveryIn Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered GrowthThe Open Form Inducer Approach for Structure-Based Drug Design.Insights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery.Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening.Targeting the redox metabolism of Plasmodium falciparum.Novel inhibitors of the Plasmodium falciparum electron transport chain.From crystal to compound: structure-based antimalarial drug discovery.Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.QSAR study on the antimalarial activity of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors.Synthesis of novel quinazolin-4(3H)-one derivatives containing the 7-oxo-1,2,4-triazolo[1,5-a]pyrimidine moiety as effective agricultural bactericides against the pathogen Xanthomonas oryzae pv. oryzae.
P2860
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P2860
Factors influencing the specificity of inhibitor binding to the human and malaria parasite dihydroorotate dehydrogenases
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Factors influencing the specif ...... dihydroorotate dehydrogenases
@ast
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en-gb
Factors influencing the specif ...... dihydroorotate dehydrogenases
@nl
type
label
Factors influencing the specif ...... dihydroorotate dehydrogenases
@ast
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en-gb
Factors influencing the specif ...... dihydroorotate dehydrogenases
@nl
prefLabel
Factors influencing the specif ...... dihydroorotate dehydrogenases
@ast
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en-gb
Factors influencing the specif ...... dihydroorotate dehydrogenases
@nl
P2093
P356
P1476
Factors influencing the specif ...... dihydroorotate dehydrogenases
@en
P2093
A Peter Johnson
Deborah Cowen
Fraser Cunningham
Glenn A McConkey
Mark R Parsons
Paul Acklam
Paul T P Bedingfield
P304
P356
10.1021/JM300157N
P407
P577
2012-06-28T00:00:00Z