Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
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Regulation of the centrosome cycleThe centriolar protein CPAP G-box: an amyloid fibril in a single domainBuilding a ninefold symmetrical barrel: structural dissections of centriole assemblyCentriole structureDissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivoThe Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication FactorStructure of a Novel O -Linked N -Acetyl-d-glucosamine ( O -GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat AdhesinsThe PLK4-STIL-SAS-6 module at the core of centriole duplicationPotential mechanisms of Zika-linked microcephalyTargeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancerSmall organelle, big responsibility: the role of centrosomes in development and disease.SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplicationThe centrosome and its duplication cycleCentriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth.Drosophila Ana1 is required for centrosome assembly and centriole elongation.A yeast two-hybrid approach for probing protein-protein interactions at the centrosome.Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.The centrosome duplication cycle in health and disease.Cartwheel assembly.The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM.Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome.The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos.A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.Structural Basis for Mitotic Centrosome Assembly in Flies.A combined 3D-SIM/SMLM approach allows centriole proteins to be localized with a precision of ∼4-5 nm.The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.STIL balancing primary microcephaly and cancer.Interaction between the C. elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly.Once and only once: mechanisms of centriole duplication and their deregulation in disease.Novel STIL Compound Heterozygous Mutations Cause Severe Fetal Microcephaly and Centriolar Lengthening.An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly.The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number.Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.Revisiting Centrioles in Nematodes-Historic Findings and Current TopicsCentrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) inEmerging Picture of Deuterosome-Dependent Centriole Amplification in MCCs
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P2860
Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
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2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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Crystal structures of the CPAP ...... ssembly and human microcephaly
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Crystal structures of the CPAP ...... ssembly and human microcephaly
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Crystal structures of the CPAP ...... ssembly and human microcephaly
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Crystal structures of the CPAP ...... ssembly and human microcephaly
@ast
Crystal structures of the CPAP ...... ssembly and human microcephaly
@en
Crystal structures of the CPAP ...... ssembly and human microcephaly
@nl
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Crystal structures of the CPAP ...... ssembly and human microcephaly
@ast
Crystal structures of the CPAP ...... ssembly and human microcephaly
@en
Crystal structures of the CPAP ...... ssembly and human microcephaly
@nl
P2093
P2860
P50
P3181
P356
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Crystal structures of the CPAP ...... ssembly and human microcephaly
@en
P2093
Christopher M Johnson
Jordan W Raff
Mark van Breugel
Matthew A Cottee
Nadine Muschalik
P2860
P304
P3181
P356
10.7554/ELIFE.01071
P407
P577
2013-09-17T00:00:00Z