Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence
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Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondiiBiochemical characterization of FIKK8--A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexansToxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice.The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection.The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.Enzyme Activity Assays for Protein Kinases: Strategies to Identify Active Substrates.A Human Proteome Array Approach to Identifying Key Host Proteins Targeted by Toxoplasma Kinase ROP18.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.
P2860
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P2860
Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence
description
2013 nî lūn-bûn
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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@ast
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@en
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@nl
type
label
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@ast
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@en
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@nl
prefLabel
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@ast
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@en
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@nl
P2093
P2860
P921
P3181
P356
P1476
Structure of the Toxoplasma go ...... t required for acute virulence
@en
P2093
Daniel A Gold
Daniel Lim
Lindsay Julien
Michael B Yaffe
Wendy Niedelman
P2860
P304
34968-34980
P3181
P356
10.1074/JBC.M113.523266
P407
P577
2013-10-15T00:00:00Z