Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

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http://www.wikidata.org/entity/Q27680375
Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondiiBiochemical characterization of FIKK8--A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexansToxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice.The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection.The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.Enzyme Activity Assays for Protein Kinases: Strategies to Identify Active Substrates.A Human Proteome Array Approach to Identifying Key Host Proteins Targeted by Toxoplasma Kinase ROP18.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.
P2860

Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

Item
http://www.wikidata.org/entity/Q27680375
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2013 nî lūn-bûn
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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
@wuu
name
Structure of the Toxoplasma go ...... t Required for Acute Virulence
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Structure of the Toxoplasma go ...... t Required for Acute Virulence
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Structure of the Toxoplasma go ...... t Required for Acute Virulence
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type
label
Structure of the Toxoplasma go ...... t Required for Acute Virulence
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Structure of the Toxoplasma go ...... t Required for Acute Virulence
@en
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@nl
prefLabel
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@ast
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@en
Structure of the Toxoplasma go ...... t Required for Acute Virulence
@nl
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Structure of the Toxoplasma go ...... t required for acute virulence
@en
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P932