Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
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Synthesis, structure and antibacterial activity of potent DNA gyrase inhibitors: N'-benzoyl-3-(4-bromophenyl)-1H-pyrazole-5-carbohydrazide derivativesRecent contributions of structure-based drug design to the development of antibacterial compounds.Repurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus.Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA.Discovery of Novel Mycobacterial DNA Gyrase B Inhibitors: In Silico and In Vitro Biological Evaluation.3D-QSAR and docking studies of flavonoids as potent Escherichia coli inhibitors.Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis.Repositioning of Endonuclear Receptors Binders as Potential Antibacterial and Antifungal Agents. Eptyloxìm: A Potential and Novel Gyrase B and Cytochrome Cyp51 Inhibitor.Biophysical Studies of Bacterial Topoisomerases Substantiate Their Binding Modes to an InhibitorThe Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases.Escherichia coli Topoisomerase IV E Subunit and an Inhibitor Binding Mode Revealed by NMR Spectroscopy.Discovery of mono- and disubstituted 1H-pyrazolo[3,4]pyrimidines and 9H-purines as catalytic inhibitors of human DNA topoisomerase IIα.Tricyclic sesquiterpenes from Vetiveria zizanoides (L.) Nash as antimycobacterial agents.Thermodynamic computational approach to capture molecular recognition in the binding of different inhibitors to the DNA gyrase B subunit from Escherichia coli.Small-Molecule Inhibitors of Pendrin Potentiate the Diuretic Action of Furosemide.Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors.Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis.NMR structural characterization of the N-terminal active domain of the gyrase B subunit fromPseudomonas aeruginosaand its complex with an inhibitorNew N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity
P2860
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P2860
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@ast
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@en
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@nl
type
label
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@ast
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@en
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@nl
prefLabel
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@ast
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@en
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@nl
P2093
P3181
P356
P1476
Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors
@en
P2093
Andrej Perdih
Dušan Turk
Gregor Anderluh
Matjaž Brvar
Miha Renko
Tom Solmajer
P304
P3181
P356
10.1021/JM300395D
P407
P577
2012-07-26T00:00:00Z