Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
about
Concerning RNA-guided gene drives for the alteration of wild populationsDiscovery and Functional Characterization of Diverse Class 2 CRISPR-Cas SystemsCRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systemsCpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas systemCRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseasesAn Overview of CRISPR-Based Tools and Their Improvements: New Opportunities in Understanding Plant-Pathogen Interactions for Better Crop ProtectionThe Rise of CRISPR/Cas for Genome Editing in Stem CellsGenome-editing Technologies for Gene and Cell TherapyHow specific is CRISPR/Cas9 really?Origins of Programmable Nucleases for Genome EngineeringDiversity of CRISPR-Cas immune systems and molecular machinesMinimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesA new age in functional genomics using CRISPR/Cas9 in arrayed library screeningSingle-Base Pair Genome Editing in Human Cells by Using Site-Specific EndonucleasesApplications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology ResearchEnabling functional genomics with genome engineeringCurrent and future prospects for CRISPR-based tools in bacteriaClassification and evolution of type II CRISPR-Cas systemsAdvances in CRISPR-Cas9 genome engineering: lessons learned from RNA interferenceOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringMaking designer mutants in model organismsCRISPR-Cas systems: Prokaryotes upgrade to adaptive immunityRNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processesLong-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system.Advances and perspectives in the application of CRISPR/Cas9 in insectsStructural basis of PAM-dependent target DNA recognition by the Cas9 endonucleaseGenetic screens and functional genomics using CRISPR/Cas9 technologySTRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognitionStructures of a CRISPR-Cas9 R-loop complex primed for DNA cleavageThe crystal structure of Cpf1 in complex with CRISPR RNASurvival and Evolution of CRISPR-Cas System in Prokaryotes and Its ApplicationsDevelopment and applications of CRISPR-Cas9 for genome engineering.A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene RegulationStructure Principles of CRISPR-Cas Surveillance and Effector ComplexesLigand-binding domains of nuclear receptors facilitate tight control of split CRISPR activityFusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modificationEngineering of temperature- and light-switchable Cas9 variantsHarnessing CRISPR-Cas9 immunity for genetic engineeringAnnotation and Classification of CRISPR-Cas Systems.CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells
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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@ast
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@en
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@nl
type
label
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@ast
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@en
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@nl
prefLabel
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@ast
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@en
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@nl
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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
@en
P2093
Feng Zhang
Hiroshi Nishimasu
Soraya I Shehata
P2860
P304
P3181
P356
10.1016/J.CELL.2014.02.001
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P577
2014-02-27T00:00:00Z