Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes

Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes

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http://www.wikidata.org/entity/Q27681748
The gatekeeper residue and beyond: homologous calcium-dependent protein kinases as drug development targets for veterinarian Apicomplexa parasites.Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.Reduced Activity of Mutant Calcium-Dependent Protein Kinase 1 Is Compensated in Plasmodium falciparum through the Action of Protein Kinase G.Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents.Antimalarial activity of kinase inhibitor, nilotinib, in vitro and in vivo.Extended-spectrum antiprotozoal bumped kinase inhibitors: A review.Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis.Invasion of hepatocytes by Plasmodium sporozoites requires cGMP-dependent protein kinase and calcium dependent protein kinase 4.Directed nucleophilic addition of phenoxides to cyclopropenes.Kinobead and Single-Shot LC-MS Profiling Identifies Selective PKD Inhibitors.Exploring the structural requirements in multiple chemical scaffolds for the selective inhibition of Plasmodium falciparum calcium-dependent protein kinase-1 (PfCDPK-1) by 3D-pharmacophore modelling, and docking studies.Plasmodial Kinase Inhibitors: License to Cure?Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
P2860

Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes

Item
http://www.wikidata.org/entity/Q27681748
description
2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Development of potent and sele ...... ssion of malaria to mosquitoes
@ast
Development of potent and sele ...... ssion of malaria to mosquitoes
@en
Development of potent and sele ...... ssion of malaria to mosquitoes
@nl
type
label
Development of potent and sele ...... ssion of malaria to mosquitoes
@ast
Development of potent and sele ...... ssion of malaria to mosquitoes
@en
Development of potent and sele ...... ssion of malaria to mosquitoes
@nl
prefLabel
Development of potent and sele ...... ssion of malaria to mosquitoes
@ast
Development of potent and sele ...... ssion of malaria to mosquitoes
@en
Development of potent and sele ...... ssion of malaria to mosquitoes
@nl
P1433
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P1476
Development of potent and sele ...... ssion of malaria to mosquitoes
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P2093
P2860
P304
P31
P356
10.1016/J.EJMECH.2013.12.048
P478
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P577
P698
P921
P932