3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3

3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3

Item
http://www.wikidata.org/entity/Q27681928
Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate CancerStructures of complexes of type 5 17β-hydroxysteroid dehydrogenase with structurally diverse inhibitors: insights into the conformational changes upon inhibitor bindingThe Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer.Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate.Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).Aldo-keto reductase family 1 member C3 (AKR1C3) is a biomarker and therapeutic target for castration-resistant prostate cancer.ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer CellsAKR1C3 as a target in castrate resistant prostate cancerAldo-Keto Reductase AKR1C1-AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy.
P2860

3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3

Item
http://www.wikidata.org/entity/Q27681928
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@ast
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@en
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@nl
type
label
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@ast
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@en
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@nl
prefLabel
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@ast
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@en
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
3-(3,4-Dihydroisoquinolin-2(1H ...... xysteroid dehydrogenase AKR1C3
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698