The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach
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Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational CoordinateEvidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolismSubstrate recognition and catalysis by GH47 α-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.Dissecting conformational contributions to glycosidase catalysis and inhibition.Conformational Behaviour of Azasugars Based on Mannuronic Acid.Systematic analysis of residual density suggests that a major limitation in well-refined X-ray structures of proteins is the omission of ordered solvent.Mannoside recognition and degradation by bacteria.Estimation of the quality of refined protein crystal structures.A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase InhibitorCarba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.Exploration of strategies for mechanism-based inhibitor design for family GH99 endo-α-1,2-mannanases.In silico analysis of interaction pattern switching in ligandreceptor binding in Golgi α-mannosidase II induced by the protonated states of inhibitors.The complete conformational free energy landscape of β-xylose reveals a two-fold catalytic itinerary for β-xylanases.Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif.
P2860
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P2860
The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach
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2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The reaction coordinate of a b ...... anical and structural approach
@ast
The reaction coordinate of a b ...... anical and structural approach
@en
The reaction coordinate of a b ...... anical and structural approach
@nl
type
label
The reaction coordinate of a b ...... anical and structural approach
@ast
The reaction coordinate of a b ...... anical and structural approach
@en
The reaction coordinate of a b ...... anical and structural approach
@nl
prefLabel
The reaction coordinate of a b ...... anical and structural approach
@ast
The reaction coordinate of a b ...... anical and structural approach
@en
The reaction coordinate of a b ...... anical and structural approach
@nl
P2093
P2860
P50
P356
P1476
The reaction coordinate of a b ...... anical and structural approach
@en
P2093
Albert Ardèvol
Aloysius Siriwardena
Carl Moreland
Harry J Gilbert
Jerome Dabin
Ting-Chou Hu
Zoran Dinev
P2860
P304
10997-11001
P356
10.1002/ANIE.201205338
P407
P50
P577
2012-09-26T00:00:00Z