Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening
about
Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMPBeta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation.Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors.Towards an understanding of the biology and targeted treatment of paediatric relapsed acute lymphoblastic leukaemia.The druggability of intracellular nucleotide-degrading enzymes.Stably transfected adherent cancer cell models with decreased expression of 5'-nucleotidase cN-II.Determination of the enzymatic activity of cytosolic 5'-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models.Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemiaScreening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?The cytosolic 5'-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells.Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism
P2860
Q27316931-984B0EE8-0EDA-4624-BB3A-5426780D90C8Q37164868-1F0C8A2E-5292-4978-964E-30BB31097396Q38151635-2E1F4E8D-C03C-4B55-A219-A933387F2A0BQ38633437-9ECD0187-BB02-4153-8B65-A03E4044DF0FQ38650970-13C5DC31-CF74-4B5D-B3B3-21C252836039Q38728094-B994AA09-6AF1-40D9-9AD9-9F2D2798BF49Q38872338-68D38932-4B86-447A-BD30-F3FD1A79CD6AQ41911065-B8A048E9-18A9-4BDA-B48E-8860AAE94021Q41976584-BCD41E3B-5956-4BEE-9B23-18784230A3FCQ41979214-F7690AEA-1823-43F6-AC6D-1FF8D3A60CB6Q57175017-4B6AE19B-907E-46CF-AA14-CCC4AF813AC8
P2860
Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Identification and characteriz ...... issued from virtual screening
@ast
Identification and characteriz ...... issued from virtual screening
@en
Identification and characteriz ...... issued from virtual screening
@nl
type
label
Identification and characteriz ...... issued from virtual screening
@ast
Identification and characteriz ...... issued from virtual screening
@en
Identification and characteriz ...... issued from virtual screening
@nl
prefLabel
Identification and characteriz ...... issued from virtual screening
@ast
Identification and characteriz ...... issued from virtual screening
@en
Identification and characteriz ...... issued from virtual screening
@nl
P50
P3181
P1476
Identification and characteriz ...... issued from virtual screening
@en
P2093
Emeline Cros-Perrial
Suzanne Peyrottes
P304
P3181
P356
10.1016/J.BCP.2012.11.024
P407
P577
2012-12-07T00:00:00Z