Fragment-based discovery of new highly substituted 1H-pyrrolo[2,3-b]- and 3H-imidazolo[4,5-b]-pyridines as focal adhesion kinase inhibitors

Fragment-based discovery of new highly substituted 1H-pyrrolo[2,3-b]- and 3H-imidazolo[4,5-b]-pyridines as focal adhesion kinase inhibitors

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http://www.wikidata.org/entity/Q27683715
The azaindole framework in the design of kinase inhibitorsFAK in cancer: mechanistic findings and clinical applicationsScope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulationFAK Inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth.Drug discovery alliances in India--indications, targets, and new chemical entities.Targeting FAK in human cancer: from finding to first clinical trials.Molecular Pathways: Endothelial Cell FAK-A Target for Cancer Treatment.Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.Exploring the interaction between human focal adhesion kinase and inhibitors: a molecular dynamic simulation and free energy calculations.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.
P2860

Fragment-based discovery of new highly substituted 1H-pyrrolo[2,3-b]- and 3H-imidazolo[4,5-b]-pyridines as focal adhesion kinase inhibitors

Item
http://www.wikidata.org/entity/Q27683715
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@ast
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@en
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@nl
type
label
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@ast
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@en
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@nl
prefLabel
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@ast
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@en
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Fragment-based discovery of ne ...... cal adhesion kinase inhibitors
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698