Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
about
Kinesin-5: cross-bridging mechanism to targeted clinical therapyRecent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyKinesin, 30 years later: Recent insights from structural studiesKinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular MachinesMechanism and regulation of kinesin-5, an essential motor for the mitotic spindle.Discovery of a novel inhibitor of kinesin-like protein KIFC1Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data.Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity.Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.Common general anesthetic propofol impairs kinesin processivity.Identification of novel scaffolds to inhibit human mitotic kinesin Eg5 targeting the second allosteric binding site using in silico methods.
P2860
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P2860
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
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2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@ast
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@en
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@nl
type
label
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@ast
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@en
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@nl
prefLabel
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@ast
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@en
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@nl
P2093
P50
P356
P1476
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
@en
P2093
Andrew Pannifer
David D Hackney
Sandeep K Talapatra
P304
P356
10.1021/JA310377D
P407
P577
2013-02-04T00:00:00Z