Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor
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Uncovering Molecular Bases Underlying Bone Morphogenetic Protein Receptor Inhibitor SelectivityMultitarget inhibitors derived from crosstalk mechanism involving VEGFR2.Whole exome sequencing in families at high risk for Hodgkin lymphoma: identification of a predisposing mutation in the KDR genePyrazoles as potential anti-angiogenesis agents: a contemporary overview.In-silico profiling of the biological activities of Amaryllidaceae alkaloids.Design, synthesis, in silico toxicity prediction, molecular docking, and evaluation of novel pyrazole derivatives as potential antiproliferative agents.Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies.The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target.Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis.Design, synthesis, in silico and antiproliferative evaluation of novel pyrazole derivatives as VEGFR-2 inhibitors.
P2860
Q28546110-9B09A072-FDE4-455F-A14C-41BA1000C2ABQ35434188-0EEBE58E-D7D1-419C-9387-164C50F5A03FQ37216463-91580E61-D648-4F8C-BF02-2518E69DF6A5Q38253652-D3E0D519-7DE5-4125-9A6B-7632BD04189EQ40082701-05A53D8C-D4B4-4024-8869-6630CBC6F260Q40277976-1CDB12EC-294E-43E4-B3C5-750CCFBED76BQ47098282-34658E87-FD4B-40F9-9FA0-6EF151C0F770Q47103458-7A58F91A-6A3D-4A1E-852D-78A71DFCCD1BQ47660354-A702474B-069F-4859-AB56-9B4BBCA02AD2Q48180043-03271429-5C9D-40D4-ACC3-908C73CCF1FB
P2860
Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
type
label
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
prefLabel
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
P2093
P1476
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
P2093
Akira Hori
Hidehisa Iwata
Hideyuki Oki
Hiroshi Miki
Kazuhiro Miwa
Kengo Okada
Naoki Miyamoto
Nozomu Sakai
Seiji Yamasaki
Shinichi Imamura
P304
P356
10.1016/J.BMC.2013.01.074
P407
P577
2013-04-15T00:00:00Z