Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor

Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor

Item
http://www.wikidata.org/entity/Q27684180
Uncovering Molecular Bases Underlying Bone Morphogenetic Protein Receptor Inhibitor SelectivityMultitarget inhibitors derived from crosstalk mechanism involving VEGFR2.Whole exome sequencing in families at high risk for Hodgkin lymphoma: identification of a predisposing mutation in the KDR genePyrazoles as potential anti-angiogenesis agents: a contemporary overview.In-silico profiling of the biological activities of Amaryllidaceae alkaloids.Design, synthesis, in silico toxicity prediction, molecular docking, and evaluation of novel pyrazole derivatives as potential antiproliferative agents.Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies.The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target.Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis.Design, synthesis, in silico and antiproliferative evaluation of novel pyrazole derivatives as VEGFR-2 inhibitors.
P2860

Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor

Item
http://www.wikidata.org/entity/Q27684180
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
type
label
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
prefLabel
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@ast
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Discovery of N-[5-({2-[(cyclop ...... potent VEGFR2 kinase inhibitor
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698