Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
about
A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.Maturation of the proteasome core particle induces an affinity switch that controls regulatory particle associationQuantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomesProteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopesStructure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.Understanding the molecular mechanism for the differential inhibitory activities of compounds against MTH1.Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis.The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3.Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core.Proteasome inhibition by bortezomib: A left hook and a right punchInhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes.Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
P2860
Q33788930-105C3863-3114-49EE-9AFF-D0BE2FAE7EE0Q35234644-24DDAED7-975F-4C74-8BD4-37F7029BD724Q36177598-E1BB0968-1544-43DF-9D5D-46D682098F0DQ36769053-EF7182E3-5E74-4011-A358-54A37B20DFC7Q37323070-08D0353C-756A-4339-B395-03E3F6A3B390Q37578809-816CF857-2AD4-43D1-AD76-1983AAC5DA3CQ37690125-E587D2FA-8350-4D89-BD4A-A94B0496FF5BQ40906092-A124CD05-6EEC-4474-9287-686587E6FC74Q41604784-98AA19D4-0802-4D37-8C0A-6A149C82CBF2Q42001818-FF22C879-01B2-4C18-96D7-3A5E067340D0Q42431910-22E61C09-B034-41C2-A2C4-BD268D1FCE69Q47119070-B6D11044-CA96-45D1-9491-3978E38A7752
P2860
Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Differential global structural ...... some induced by ligand binding
@ast
Differential global structural ...... some induced by ligand binding
@en
Differential global structural ...... some induced by ligand binding
@nl
type
label
Differential global structural ...... some induced by ligand binding
@ast
Differential global structural ...... some induced by ligand binding
@en
Differential global structural ...... some induced by ligand binding
@nl
prefLabel
Differential global structural ...... some induced by ligand binding
@ast
Differential global structural ...... some induced by ligand binding
@en
Differential global structural ...... some induced by ligand binding
@nl
P2093
P2860
P3181
P356
P1476
Differential global structural ...... some induced by ligand binding
@en
P2093
Marcelino Arciniega
Oliver F Lange
Robert Huber
P2860
P304
P3181
P356
10.1073/PNAS.1408018111
P407
P577
2014-07-01T00:00:00Z