Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
about
Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities.From rabbit antibody repertoires to rabbit monoclonal antibodiesA monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.Humanization of rabbit monoclonal antibodies via grafting combined Kabat/IMGT/Paratome complementarity-determining regions: Rationale and examples.Evading pre-existing anti-hinge antibody binding by hinge engineering.Tumor evasion of humoral immunity mediated by proteolytic impairment of antibody triggered immune effector function.Molecular characterization of human anti-hinge antibodies derived from single cell cloning of normal human B cells.Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
P2860
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P2860
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@ast
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@en
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@nl
type
label
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@ast
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@en
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@nl
prefLabel
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@ast
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@en
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@nl
P2093
P2860
P50
P356
P1433
P1476
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge
@en
P2093
Gary L Gilliland
Jinquan Luo
Michelle Kinder
Raymond W Sweet
Robert E Jordan
Thomas J Malia
P2860
P304
P356
10.1002/PROT.24545
P407
P577
2014-04-16T00:00:00Z