Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
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Ubiquitin modificationsTNF biology, pathogenic mechanisms and emerging therapeutic strategiesRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINLinear ubiquitination signals in adaptive immune responsesDeubiquitinases: Novel Therapeutic Targets in Immune Surveillance?Molecular basis for specificity of the Met1-linked polyubiquitin signalLinear ubiquitination in immunityCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingThe Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and AutoimmunityBiallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory diseaseControl of p97 function by cofactor bindingNF-κB Pathway in Autoinflammatory Diseases: Dysregulation of Protein Modifications by Ubiquitin Defines a New Category of Autoinflammatory Diseases.The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder.The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression.Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain FormationStructure and function of the AAA+ ATPase p97/Cdc48p.p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity.Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.Met1-linked ubiquitination in immune signalling.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.Roles of the NF-κB Pathway in B-Lymphocyte Biology.Mechanisms of regulation and diversification of deubiquitylating enzyme function.Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.The increasing complexity of the ubiquitin code.Post-translational control of NF-κB signaling by ubiquitination.Lessons from characterization and treatment of the autoinflammatory syndromes.CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different.Linear ubiquitin chains: enzymes, mechanisms and biologyThe Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97.Ubiquitin enzymes in the regulation of immune responses.SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC SignalingGenomics, Biology, and Human Illness: Advances in the Monogenic Autoinflammatory Diseases.
P2860
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P2860
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@ast
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@en
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@nl
type
label
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@ast
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@en
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@nl
prefLabel
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@ast
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@en
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@nl
P2093
P921
P3181
P1433
P1476
Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling
@en
P2093
Ligia C Gomes
Masato Akutsu
Masato Kawasaki
Michael H Olma
Veronique Schaeffer
P304
P3181
P356
10.1016/J.MOLCEL.2014.03.016
P407
P50
P577
2014-05-08T00:00:00Z