KIF14 binds tightly to microtubules and adopts a rigor-like conformation
about
The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movementKinesin, 30 years later: Recent insights from structural studiesCrystal structures of MBP fusion proteinsKinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular MachinesStructural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity.High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generationThe kinesin KIF14 is overexpressed in medulloblastoma and downregulation of KIF14 suppressed tumor proliferation and induced apoptosis.The structural switch of nucleotide-free kinesin.The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.Mutations of KIF14 Cause Primary Microcephaly by Impairing Cytokinesis.Kinesin motility is driven by subdomain dynamics.Biallelic variants in KIF14 cause intellectual disability with microcephaly.Kinesin expands and stabilizes the GDP-microtubule lattice.Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer
P2860
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P2860
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@ast
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@en
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@nl
type
label
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@ast
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@en
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@nl
prefLabel
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@ast
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@en
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@nl
P2093
P1476
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
@en
P2093
Ana B Asenjo
Benjamin H Kwok
Hernando Sosa
John S Allingham
Kaleem Atchia
Kritica Arora
Lama Talje
Monika Joshi
Parker Andersen
P304
P356
10.1016/J.JMB.2014.05.030
P407
P577
2014-08-26T00:00:00Z