Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
about
Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active siteIndolo-phakellins as β5-specific noncovalent proteasome inhibitorsA Minimal β-Lactone Fragment for Selective β5c or β5i Proteasome InhibitorsIdentification of a β1/β2-specific sulfonamide proteasome ligand by crystallographic screeningSubunit specific inhibitors of proteasomes and their potential for immunomodulationDiscovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit.Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancersBlockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes.Recent advances and future directions in targeting the secretory apparatus in multiple myeloma.Multigram-scale Synthesis of Enantiopure 3,3-Difluoroproline.Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib.A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i.Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target(Immuno)proteasomes as therapeutic target in acute leukemia.Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome.Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome.Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome.A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.
P2860
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P2860
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
description
2014 nî lūn-bûn
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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@ast
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@en
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@nl
type
label
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@ast
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@en
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@nl
prefLabel
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@ast
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@en
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@nl
P2093
P3181
P356
P1476
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes
@en
P2093
Alexei F Kisselev
Bo-Tao Xin
Christoph Driessen
Eva J van Rooden
Eva M Huber
Gerjan de Bruin
Gijsbert A van der Marel
Herman S Overkleeft
Karol Al-Ayed
Kyung-Bo Kim
P304
P3181
P356
10.1021/JM500716S
P407
P577
2014-07-24T00:00:00Z