Crystal structure and mechanistic investigation of the twister ribozyme
about
Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAsChemistry and Biology of Self-Cleaving RibozymesNew classes of self-cleaving ribozymes revealed by comparative genomics analysisThe Routes of Emergence of Life from LUCA during the RNA and Viral World: A ConspectusUnwinding the twister ribozyme: from structure to mechanism.In-line alignment and Mg²⁺ coordination at the cleavage site of the env22 twister ribozyme.Biochemical analysis of pistol self-cleaving ribozymes.Biochemical analysis of hatchet self-cleaving ribozymes.Crystal structure of the Varkud satellite ribozyme.Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulationsHigh-throughput assay and engineering of self-cleaving ribozymes by sequencing.Heavy atom labeled nucleotides for measurement of kinetic isotope effectsDSSR: an integrated software tool for dissecting the spatial structure of RNA.A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.Ribozyme Catalysis with a Twist: Active State of the Twister Ribozyme in Solution Predicted from Molecular Simulation.Molecular Dynamics Study of Twister Ribozyme: Role of Mg(2+) Ions and the Hydrogen-Bonding Network in the Active Site.Model for the Functional Active State of the TS Ribozyme from Molecular Simulation.Strategies for Characterization of Enzymatic Nucleic Acids.Pseudoknot Formation Seeds the Twister Ribozyme Cleavage Reaction Coordinate.Divalent Metal Ion Activation of a Guanine General Base in the Hammerhead Ribozyme: Insights from Molecular Simulations.Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes.The structure of a nucleolytic ribozyme that employs a catalytic metal ion.Mechanistic Debris Generated by Twister Ribozymes.The synthesis of 15N(7)-Hoogsteen face-labeled adenosine phosphoramidite for solid-phase RNA synthesis.Twister ribozymes as highly versatile expression platforms for artificial riboswitches.Facile synthesis of a 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis.High-Throughput Mutational Analysis of a Twister Ribozyme.Nucleic acids: function and potential for abiogenesis.Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs.Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Occurrence and stability of lone pair-π stacking interactions between ribose and nucleobases in functional RNAs.Metals induce transient folding and activation of the twister ribozyme.Atom-Specific Mutagenesis Reveals Structural and Catalytic Roles for an Active-Site Adenosine and Hydrated Mg2+ in Pistol Ribozymes.Evidence of a General Acid/Base Catalysis Mechanism in the 8-17 DNAzyme.
P2860
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P2860
Crystal structure and mechanistic investigation of the twister ribozyme
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Crystal structure and mechanistic investigation of the twister ribozyme
@ast
Crystal structure and mechanistic investigation of the twister ribozyme
@en
Crystal structure and mechanistic investigation of the twister ribozyme
@nl
type
label
Crystal structure and mechanistic investigation of the twister ribozyme
@ast
Crystal structure and mechanistic investigation of the twister ribozyme
@en
Crystal structure and mechanistic investigation of the twister ribozyme
@nl
prefLabel
Crystal structure and mechanistic investigation of the twister ribozyme
@ast
Crystal structure and mechanistic investigation of the twister ribozyme
@en
Crystal structure and mechanistic investigation of the twister ribozyme
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure and mechanistic investigation of the twister ribozyme
@en
P2093
David M J Lilley
Scott A McPhee
Timothy J Wilson
P2860
P2888
P304
P3181
P356
10.1038/NCHEMBIO.1587
P577
2014-09-01T00:00:00Z
P6179
1039063181