RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association
about
Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitroA Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.Neuropilin-1 is a glial cell line-derived neurotrophic factor receptor in glioblastoma.The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer.Structure and biophysical characterisation of the human full-length Neurturin-GFRa2 complex - a role for heparan sulfate in signalling.Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine kinase.Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer.Small-Molecule Ligands as Potential GDNF Family Receptor Agonists.Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands
P2860
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P2860
RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@ast
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@en
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@nl
type
label
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@ast
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@en
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@nl
prefLabel
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@ast
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@en
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@nl
P2093
P1433
P1476
RET recognition of GDNF-GFRα1 ...... rane-proximal self-association
@en
P2093
Andrew G Purkiss
Edward P Morris
Emily M Burns
Fabienne Beuron
Kerry M Goodman
Massimo Santoro
Neil Q McDonald
Phillip P Knowles
Roger George
Svend Kjær
P304
P356
10.1016/J.CELREP.2014.08.040
P577
2014-09-18T00:00:00Z