Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors - Wikidata - awgldk - TriplyDB

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

http://www.wikidata.org/entity/Q27701538

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Process of Fragment-Based Lead Discovery-A Perspective from NMR NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains A Chemical Probe for the ATAD2 Bromodomain Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.Suppression of ATAD2 inhibits hepatocellular carcinoma progression through activation of p53- and p38-mediated apoptotic signaling Progress in the Development of non-BET Bromodomain Chemical Probes.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Structural features and inhibitors of bromodomains.Bromodomain inhibitors and cancer therapy: From structures to applications.Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks.Chemical probes and inhibitors of bromodomains outside the BET family.ATAD2 in cancer: a pharmacologically challenging but tractable target.The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes.The identification of new ATAD2 bromodomain inhibitors: the application of combined ligand and structure-based virtual screening.Patent Highlights June-July 2017.Identifying Small-Molecule Binding Sites for Epigenetic Proteins at Domain-Domain Interfaces.Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple).A Chemical Probe for the ATAD2 Bromodomain

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Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

http://www.wikidata.org/entity/Q27701538

description

2015 nî lūn-bûn

@nan

2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@ast

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@en

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@nl

type

label

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@ast

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@en

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@nl

prefLabel

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@ast

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@en

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

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ACS.JMEDCHEM.5B00772

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Journal of Medicinal Chemistry

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Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors

@en

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Amanda J Emmons

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Andy D Roberts

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Angela M Bridges

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Bernadette H Mouzon

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Bhumika V Karamshi

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Chris Wellaway

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Chun-wa Chung

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Clement Douault

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Darren J Mitchell

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David P Dixon

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5649-73

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scholarly article

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4829984

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10.1021/ACS.JMEDCHEM.5B00772

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14

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58

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Anne-Marie Michon

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2015-07-23T00:00:00Z

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26155854

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