Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies

Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies

Item
http://www.wikidata.org/entity/Q27703241
Non-equilibrium hydrogen exchange for determination of H-bond strength and water accessibility in solid proteins.Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases.Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity.Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design
P2860

Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies

Item
http://www.wikidata.org/entity/Q27703241
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Kinetic and Structural Insight ...... ional and Experimental Studies
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Kinetic and Structural Insight ...... ional and Experimental Studies
@en
Kinetic and Structural Insight ...... ional and Experimental Studies
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type
label
Kinetic and Structural Insight ...... ional and Experimental Studies
@ast
Kinetic and Structural Insight ...... ional and Experimental Studies
@en
Kinetic and Structural Insight ...... ional and Experimental Studies
@nl
prefLabel
Kinetic and Structural Insight ...... ional and Experimental Studies
@ast
Kinetic and Structural Insight ...... ional and Experimental Studies
@en
Kinetic and Structural Insight ...... ional and Experimental Studies
@nl
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P1476
P2093
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P478
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P577
P698
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P1433
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Kinetic and Structural Insight ...... ional and Experimental Studies
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P2093
P304
P31
P356
10.1021/ACS.JMEDCHEM.5B01643
P407
P433
P478
P50
P577
P698