The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM
about
Detection of substrate-dependent conformational changes in the P450 fold by nuclear magnetic resonance.Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURESSolution Structural Ensembles of Substrate-Free Cytochrome P450 camF429 Regulation of Tunnels in Cytochrome P450 2B4: A Top Down Study of Multiple Molecular Dynamics SimulationsGeauxDock: Accelerating Structure-Based Virtual Screening with Heterogeneous ComputingEvolutionary history of a specialized p450 propane monooxygenaseRedox potential control by drug binding to cytochrome P450 3A4Flavonoid 6-hydroxylase from soybean (Glycine max L.), a novel plant P-450 monooxygenase.Antagonistic effects of hydrostatic pressure and osmotic pressure on cytochrome P-450cam spin transition.Elucidating the role of the proximal cysteine hydrogen-bonding network in ferric cytochrome P450cam and corresponding mutants using magnetic circular dichroism spectroscopy.Interactions of cytochrome P450s with their ligands.Protein dynamics in cytochrome P450 molecular recognition and substrate specificity using 2D IR vibrational echo spectroscopy.Spring-loading the active site of cytochrome P450cam.P450 structures and oxidative metabolism of xenobiotics.A single amino acid substitution (F363I) converts the regiochemistry of the spearmint (-)-limonene hydroxylase from a C6- to a C3-hydroxylaseCytochrome P450: what have we learned and what are the future issues?Identification of a functional water channel in cytochrome P450 enzymes.Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases.NADH reduction of nitroaromatics as a probe for residual ferric form high-spin in a cytochrome P450.Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study.Crystallization and preliminary x-ray diffraction analysis of P450terp and the hemoprotein domain of P450BM-3, enzymes belonging to two distinct classes of the cytochrome P450 superfamilyS K-edge XAS and DFT calculations on cytochrome P450: covalent and ionic contributions to the cysteine-Fe bond and their contribution to reactivity.Conformational plasticity and structure/function relationships in cytochromes P450.Optimized expression and catalytic properties of a wheat obtusifoliol 14alpha-demethylase (CYP51) expressed in yeast. Complementation of erg11Delta yeast mutants by plant CYP51.Conformational Heterogeneity and the Affinity of Substrate Molecular Recognition by Cytochrome P450cam.Chemical inactivation of the cinnamate 4-hydroxylase allows for the accumulation of salicylic acid in elicited cells.Cytochromes P450: their active-site structure and mechanism of oxidation.Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes.Controlling the regiospecificity and coupling of cytochrome P450cam: T185F mutant increases coupling and abolishes 3-hydroxynorcamphor product.NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes.A critical role of protein-bound water in the catalytic cycle of cytochrome P-450 camphor.Stereoselective hydroxylation of norcamphor by cytochrome P450cam. Experimental verification of molecular dynamics simulations.
P2860
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P2860
The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM
description
1989 nî lūn-bûn
@nan
1989 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
The structural basis for subst ...... librium in cytochrome P-450CAM
@ast
The structural basis for subst ...... librium in cytochrome P-450CAM
@en
The structural basis for subst ...... librium in cytochrome P-450CAM
@nl
type
label
The structural basis for subst ...... librium in cytochrome P-450CAM
@ast
The structural basis for subst ...... librium in cytochrome P-450CAM
@en
The structural basis for subst ...... librium in cytochrome P-450CAM
@nl
prefLabel
The structural basis for subst ...... librium in cytochrome P-450CAM
@ast
The structural basis for subst ...... librium in cytochrome P-450CAM
@en
The structural basis for subst ...... librium in cytochrome P-450CAM
@nl
P3181
P356
P1433
P1476
The structural basis for subst ...... librium in cytochrome P-450CAM
@en
P2093
P304
P3181
P356
10.1021/BI00428A077
P407
P577
1989-01-24T00:00:00Z