Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
about
Characterization of non-heme iron aliphatic halogenase WelO5* fromHapalosiphon welwitschiiIC-52-3: Identification of a minimal protein sequence motif that confers enzymatic chlorination specificity in the biosynthesis of welwitindolelinones.Discovery of a Calcium-Dependent Enzymatic Cascade for the Selective Assembly of Hapalindole-Type Alkaloids: On the Biosynthetic Origin of Hapalindole U.Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Divergent mechanisms of iron-containing enzymes for hydrocarbon biosynthesis.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Vanadium Chloroperoxidases: The Missing Link in the Formation of Chlorinated Compounds and Chloroform in the Terrestrial Environment?Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes.Formation and structure of the ferryl [Fe[double bond, length as m-dash]O] intermediate in the non-haem iron halogenase SyrB2: classical and QM/MM modelling agree.Frontier Molecular Orbital Contributions to Chlorination versus Hydroxylation Selectivity in the Non-Heme Iron Halogenase SyrB2.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase.Structure-Guided Reprogramming of a Hydroxylase To Halogenate Its Small Molecule Substrate.Observation of Radical Rebound in a Mononuclear Nonheme Iron Model Complex.Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering.Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosyntheses
P2860
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P2860
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
description
2016 nî lūn-bûn
@nan
2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@ast
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@en
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@nl
type
label
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@ast
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@en
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@nl
prefLabel
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@ast
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@en
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@nl
P2093
P2860
P356
P1476
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
@en
P2093
Ailiena O Maggiolo
Amie K Boal
Nikhil R Ananth
P2860
P2888
P304
P356
10.1038/NCHEMBIO.2112
P577
2016-08-01T00:00:00Z
P6179
1041119111