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Speciation of precious metal anti-cancer complexes by NMR spectroscopyReporting biological assay screening results for maximum impactChemical databases: curation or integration by user-defined equivalence?Expanding opportunities for mining bioactive chemistry from patentsThe controversial world of sirtuinsSmall molecule inhibitors of the HIV-1 virulence factor, NefPersonalized HIV therapy to control drug resistanceTransporter assays and assay ontologies: useful tools for drug discoveryTarget discovery from protein databases: challenges for curationExploiting transferrin receptor for delivering drugs across the blood-brain barrierUltrasound-mediated drug delivery to the brain: principles, progress and prospectsKinetic analysis of drug-protein interactions by affinity chromatographyCell-based assays to support the profiling of small molecules with histone methyltransferase and demethylase modulatory activityTranslational pharmacokinetics and pharmacodynamics of monoclonal antibodiesMeasuring blood-brain barrier penetration using the NeuroCart, a CNS test batteryProfiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitorsThe semantic web and knowledge gridsAdvances in virtual screeningMycobacterial genetics in target validation.Data-driven computer aided synthesis design.Complementary molecular imaging technologies: High resolution SPECT, PET and MRI.Light, sound, chemistry… action: state of the art optical methods for animal imaging.Resistance to Raf inhibition in cancer.Use of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions.Overcoming antifungal resistance.A high throughput flow cytometric assay platform targeting transporter inhibitionMulti-objective optimization methods in drug design.In silico antitarget screening.Label-Free Receptor Assays.Zebrafish based small molecule screens for novel DMD drugs.Very large virtual compound spaces: construction, storage and utility in drug discovery.Technology combination to address GPCR allosteric modulator drug-discovery pitfalls.Chemogenomics of allosteric binding sites in GPCRs.Recent development of RNAi in drug target discovery and validation.Proteomics: how to control highly dynamic patterns of millions of molecules and interpret changes correctly?Reverse pharmacology and the de-orphanization of 7TM receptors.Tapping, pulling, probing: atomic force microscopy in drug discovery.Drug-like properties: guiding principles for design - or chemical prejudice?Fast similarity searching and screening hit analysis.Lead identification in post-genomics: computers as a complementary alternative.
P1433
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P1433
description
journal
@en
revista científica
@es
wetenschappelijk tijdschrift van Elsevier
@nl
wissenschaftliche Fachzeitschrift
@de
name
Drug discovery today. Technologies
@ast
Drug discovery today. Technologies
@en
Drug discovery today. Technologies
@es
Drug discovery today. Technologies
@nl
type
label
Drug discovery today. Technologies
@ast
Drug discovery today. Technologies
@en
Drug discovery today. Technologies
@es
Drug discovery today. Technologies
@nl
altLabel
Drug Discov Today Technol
@en
prefLabel
Drug discovery today. Technologies
@ast
Drug discovery today. Technologies
@en
Drug discovery today. Technologies
@es
Drug discovery today. Technologies
@nl
P3181
P1055
P1156
P123
P1277
P1476
Drug discovery today. Technologies
@en
P236
P3181
P5963
drug-discovery-today-technologies