Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR - Wikidata - awgldk - TriplyDB

Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR

Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR

http://www.wikidata.org/entity/Q27725743

about

Advances of small molecule targeting of kinases.Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells.A Bioorganometallic Approach to Study Histidine Kinase Autophosphorylations.Discovery of EGF Receptor Inhibitors That Are Selective for the d746-750/T790M/C797S Mutant through Structure-Based de Novo Design.Characterization of Covalent-Reversible EGFR Inhibitors.C797S Resistance: The Undruggable EGFR Mutation in Non-Small Cell Lung Cancer?Overcoming EGFR-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

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P2860

Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR

http://www.wikidata.org/entity/Q27725743

description

2016 nî lūn-bûn

@nan

2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

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name

Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

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P1433

Angewandte Chemie International Edition

P1476

Insight into the Inhibition of ...... Receptor Tyrosine Kinase EGFR

@en

P2093

Christian Becker

http://www.w3.org/2001/XMLSchema#string

Julia Ketzer

http://www.w3.org/2001/XMLSchema#string

Julian Engel

http://www.w3.org/2001/XMLSchema#string

Laxmikanth Kollipara

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Marina Keul

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Sebastian Bauer

http://www.w3.org/2001/XMLSchema#string

P2860

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR

Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial.

AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer.

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10909-12

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scholarly article

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10.1002/ANIE.201605011

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36

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55

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P50

René P. Zahedi

Thomas Mühlenberg

Carsten Schultz-Fademrecht

P577

2016-08-26T00:00:00Z

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P698

27496389

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