Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution
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Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopyRecent Advances in Developing Small Molecules Targeting Nucleic AcidDNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2)Crystal structure of an RNA{middle dot}DNA hybrid reveals intermolecular intercalation: Dimer formation by base-pair swappingCrystal structure of trioxacarcin A covalently bound to DNAFacile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adductSolution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalatorCrystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand bindingMolecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG)Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslinkA continuous transition from A-DNA to B-DNA in the 1:1 complex between nogalamycin and the hexamer dCCCGGGBinding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexesPremelting base pair opening probability and drug binding constant of a daunomycin-poly d(GCAT).poly d(ATGC) complexNMR investigation of the complexation of daunomycin with deoxytetranucleotides of different base sequence in aqueous solution.Molecular mechanisms and kinetics between DNA and DNA binding ligands.DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores.Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.Model of the interactions of calichemicin gamma 1 with a DNA fragment from pBR322.Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.Femtosecond dynamics of a drug-protein complex: daunomycin with Apo riboflavin-binding protein.The anticancer drug-DNA complex: femtosecond primary dynamics for anthracycline antibiotics function.Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcriptsMolecular dynamics of anthraquinone DNA intercalators with polyethylene glycol side chains.Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity.Enthalpy-entropy compensations in drug-DNA binding studies.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Allosteric, chiral-selective drug binding to DNA.The DnrN protein of Streptomyces peucetius, a pseudo-response regulator, is a DNA-binding protein involved in the regulation of daunorubicin biosynthesis.The impact of DNA intercalators on DNA and DNA-processing enzymes elucidated through force-dependent binding kinetics.Determining DNA supercoiling enthalpy by isothermal titration calorimetrySynthesis and DNA-binding affinity studies of glycosylated intercalators designed as functional mimics of the anthracycline antibioticsProbing the relative orientation of molecules bound to DNA through controlled interference using second-harmonic generationA pseudocatenane structure formed between DNA and A cyclic bisintercalator.CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity.Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes.Structure of nogalamycin bound to a DNA hexamer.Study on the interaction of an anthracycline disaccharide with DNA by spectroscopic techniques and molecular modeling.31P NMR study of daunorubicin-d(CGTACG) complex in solution. Evidence of the intercalation sites.On the possible mechanism of recognition of DNA base sequence by steroid hormones.
P2860
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P2860
Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution
description
1987 nî lūn-bûn
@nan
1987 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
name
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@ast
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@en
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@nl
type
label
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@ast
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@en
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@nl
prefLabel
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@ast
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@en
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@nl
P2093
P3181
P356
P1433
P1476
Interactions between an anthra ...... GpTpApCpG) at 1.2-A resolution
@en
P2093
P304
P3181
P356
10.1021/BI00378A025
P407
P577
1987-02-24T00:00:00Z