Involvement of Tyr24 and Trp108 in substrate binding and substrate specificity of glycolate oxidase
about
Active site and loop 4 movements within human glycolate oxidase: implications for substrate specificity and drug designStructure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazoleThe substrate tolerance of alcohol oxidasesThe x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenationStructural evidence: a single charged residue affects substrate binding in cytochrome P450 BM-3Speeding up the product release: a second-sphere contribution from Tyr191 to the reactivity of L-lactate oxidase revealed in crystallographic and kinetic studies of site-directed variantsThree-dimensional structures of glycolate oxidase with bound active-site inhibitors.Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr(215) in Aerococcus viridans lactate oxidase.Experimental evidence for a hydride transfer mechanism in plant glycolate oxidase catalysisThe 2.1 A structure of Aerococcus viridans L-lactate oxidase (LOX)Identification of the naturally occurring flavin of nitroalkane oxidase from fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form.Involvement of ionizable groups in catalysis of human liver glycolate oxidase.Roles of key active-site residues in flavocytochrome P450 BM3Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism.The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from baker's yeast). Comparison between the Y254F and Y254L mutant proteins.Cyanobacterial lactate oxidases serve as essential partners in N2 fixation and evolved into photorespiratory glycolate oxidases in plants.Plant and animal glycolate oxidases have a common eukaryotic ancestor and convergently duplicated to evolve long-chain 2-hydroxy acid oxidases.A basic phenylalanine-rich oligo-peptide causes antibody cross-reactivity.Quantifying the evolutionary divergence of protein structures: the role of function change and function conservation.
P2860
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P2860
Involvement of Tyr24 and Trp108 in substrate binding and substrate specificity of glycolate oxidase
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@ast
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@en
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@nl
type
label
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@ast
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@en
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@nl
prefLabel
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@ast
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@en
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@nl
P2860
P50
P3181
P1433
P1476
Involvement of Tyr24 and Trp10 ...... ecificity of glycolate oxidase
@en
P2093
K Stenberg
P2860
P304
P3181
P356
10.1111/J.1432-1033.1995.00408.X
10.1111/J.1432-1033.1995.TB20278.X
P407
P577
1995-03-01T00:00:00Z