The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase
about
Molecular characterization of 3-phosphoglycerate dehydrogenase deficiency--a neurometabolic disorder associated with reduced L-serine biosynthesis.A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduriaBinding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: Implications for allosteric regulationCtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fissionA novel NAD-binding protein revealed by the crystal structure of 2,3-diketo-L-gulonate reductase (YiaK)The effect of hinge mutations on effector binding and domain rotation in Escherichia coli D-3-phosphoglycerate dehydrogenaseStructures of open (R) and close (T) states of prephenate dehydratase (PDT)—Implication of allosteric regulation by l-phenylalanineStructural Analysis of Substrate and Effector Binding in Mycobacterium tuberculosis d -3-Phosphoglycerate Dehydrogenase † ‡Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogansThe C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT DomainCrystal Structures of Phosphite Dehydrogenase Provide Insights into Nicotinamide Cofactor RegenerationThe Solution Structure of the Regulatory Domain of Tyrosine HydroxylaseCrystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysineCrystal structure of a hypothetical protein, TTHA0829 from Thermus thermophilus HB8, composed of cystathionine-β-synthase (CBS) and aspartate-kinase chorismate-mutase tyrA (ACT) domainsAnalysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenaseCloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenaseA novel mechanism for substrate inhibition in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenaseCrystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesisDiscovery of novel allosteric effectors based on the predicted allosteric sites for Escherichia coli D-3-phosphoglycerate dehydrogenaseStructure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric CommunicationSummarizing and exploring data of a decade of cytokinin-related transcriptomicsX-ray Scattering Studies of Protein Structural Dynamics.The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins.Specific interactions at the regulatory domain-substrate binding domain interface influence the cooperativity of inhibition and effector binding in Escherichia coli D-3-phosphoglycerate dehydrogenase.Transient kinetic analysis of the interaction of L-serine with Escherichia coli D-3-phosphoglycerate dehydrogenase reveals the mechanism of V-type regulation and the order of effector bindingThe contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase.The ACR11 encodes a novel type of chloroplastic ACT domain repeat protein that is coordinately expressed with GLN2 in Arabidopsis.Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production.V490M, a common mutation in 3-phosphoglycerate dehydrogenase deficiency, causes enzyme deficiency by decreasing the yield of mature enzyme.Composite structural motifs of binding sites for delineating biological functions of proteins.Contrasting catalytic and allosteric mechanisms for phosphoglycerate dehydrogenases.Quantitative relationships of site to site interaction in Escherichia coli D-3-phosphoglycerate dehydrogenase revealed by asymmetric hybrid tetramers.The mechanism of velocity modulated allosteric regulation in D-3-phosphoglycerate dehydrogenase. Cross-linking adjacent regulatory domains with engineered disulfides mimics effector binding.A model for the regulation of D-3-phosphoglycerate dehydrogenase, a Vmax-type allosteric enzyme.Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine.Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active siteTransient kinetic analysis of L-serine interaction with Escherichia coli D-3-phosphoglycerate dehydrogenase containing amino acid mutations in the hinge regions.Physiological analysis of the stringent response elicited in an extreme thermophilic bacterium, Thermus thermophilus.Expression, purification and preliminary crystallographic analysis of Rv3002c, the regulatory subunit of acetolactate synthase (IlvH) from Mycobacterium tuberculosisThe relationship between effector binding and inhibition of activity in D-3-phosphoglycerate dehydrogenase.
P2860
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P2860
The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@ast
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@en
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@nl
type
label
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@ast
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@en
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@nl
prefLabel
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@ast
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@en
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@nl
P2093
P2860
P3181
P356
P1476
The allosteric ligand site in ...... phosphoglycerate dehydrogenase
@en
P2093
D J Schuller
L J Banaszak
P2860
P3181
P356
10.1038/NSB0195-69
P577
1995-01-01T00:00:00Z