Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
about
Quaternary structure built from subunits combining NMR and small-angle x-ray scattering data.Normal modes for predicting protein motions: a comprehensive database assessment and associated Web toolBepridil opens the regulatory N-terminal lobe of cardiac troponin CPhenothiazines inhibit S100A4 function by inducing protein oligomerizationCharacterization of the Photophysical, Thermodynamic, and Structural Properties of the Terbium(III)-DREAM Complex.Characterisation of two calmodulin-like proteins from the liver fluke, Fasciola hepatica.Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist.Structural insights into a 20.8-kDa tegumental-allergen-like (TAL) protein from Clonorchis sinensis.Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulinCalcium binding decreases the stokes radius of calmodulin and mutants R74A, R90A, and R90GOpposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulinOptimized torsion-angle normal modes reproduce conformational changes more accurately than cartesian modes.Structure-activity relationships for the antifungal activity of selective estrogen receptor antagonists related to tamoxifenNMR and molecular dynamics studies of the interaction of melatonin with calmodulin.Conformational heterogeneity of the calmodulin binding interface.Orientation of the essential light chain region of myosin in relaxed, active, and rigor muscleSingle-Molecule FRET States, Conformational Interchange, and Conformational Selection by Dye Labels in CalmodulinStructural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin.Hydrogels Constructed from Engineered Proteins.Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering.FhCaBP2: a Fasciola hepatica calcium-binding protein with EF-hand and dynein light chain domains.Postsynaptic clustering and activation of Pyk2 by PSD-95Two-Dimensional NMR Lineshape Analysis.A molecular dynamics study of Ca(2+)-calmodulin: evidence of interdomain coupling and structural collapse on the nanosecond timescale.Comparative biochemical analysis of three members of the Schistosoma mansoni TAL family: Differences in ion and drug binding properties.The binding of myristoylated N-terminal nonapeptide from neuro-specific protein CAP-23/NAP-22 to calmodulin does not induce the globular structure observed for the calmodulin-nonmyristylated peptide complex.Interlobe communication in multiple calcium-binding site mutants of Drosophila calmodulin.Trifluoperazine regulation of calmodulin binding to Fas: a computational study.Ca2+-bound calmodulin forms a compact globular structure on binding four trifluoperazine molecules in solution.Crystallization and preliminary diffraction analysis of Ca(2+)-calmodulin-drug and apocalmodulin-drug complexes.Predicting drug-target interactions using probabilistic matrix factorization.FhCaBP4: a Fasciola hepatica calcium-binding protein with EF-hand and dynein light chain domains.The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug.Locking regulatory myosin in the off-state with trifluoperazine.
P2860
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P2860
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@ast
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@en
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@nl
type
label
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@ast
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@en
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@nl
prefLabel
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@ast
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@en
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@nl
P2093
P3181
P356
P1433
P1476
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex
@en
P2093
P304
P3181
P356
10.1021/BI00255A006
P407
P577
1994-12-27T00:00:00Z