Penicillin acylase has a single-amino-acid catalytic centre
about
Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginineNovel insights into eukaryotic γ-glutamyltranspeptidase 1 from the crystal structure of the glutamate-bound human enzymeX-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene clusterIdentification of a novel amidase motif in neutral ceramidaseAnalysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysisThe enzymes of bacterial census and censorshipCrystal structure of penicillin G acylase from the bro1 mutant strain ofprovidencia rettgeriPrecursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase familyStructure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin CAffinity alkylation of the Trp-B4 residue of the beta -subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp. 130A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical studyMutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate bindingCrystallographic Snapshot of a Productive Glycosylasparaginase–Substrate ComplexStructural constraints on protein self-processing in L-aspartate- -decarboxylaseThe mechanism of autocatalytic activation of plant-type L-asparaginasesInitial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallographyThe quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocketCrystal structure of the halotolerant gamma-glutamyltranspeptidase from Bacillus subtilis in complex with glutamate reveals a unique architecture of the solvent-exposed catalytic pocketAutoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and CatalysisStructural and Kinetic Characterization of Guinea Pig l -Asparaginase Type IIIStructure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activityExploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT.Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtCStructure and function of the glutamine phosphoribosylpyrophosphate amidotransferase glutamine site and communication with the phosphoribosylpyrophosphate siteThree-dimensional structure of human lysosomal aspartylglucosaminidaseCrystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicingCrystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysisBiodegradation of aromatic compounds by Escherichia coliUnconventional serine proteases: variations on the catalytic Ser/His/Asp triad configurationThe ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine proteaseThe ubiquitin-proteasome pathway and proteasome inhibitorsQuorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1.The role of alpha-amino group of the N-terminal serine of beta subunit for enzyme catalysis and autoproteolytic activation of glutaryl 7-aminocephalosporanic acid acylase.Why does threonine, and not serine, function as the active site nucleophile in proteasomes?Evolution of an acylase active on cephalosporin CNew active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase.Overexpression and mass spectrometry analysis of mature human acid ceramidase.Cloning, overexpression, and characterization of a novel thermostable penicillin G acylase from Achromobacter xylosoxidans: probing the molecular basis for its high thermostabilityAspartic peptide hydrolases in Salmonella enterica serovar typhimurium.Divergence and convergence in enzyme evolution.
P2860
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P2860
Penicillin acylase has a single-amino-acid catalytic centre
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Penicillin acylase has a single-amino-acid catalytic centre
@ast
Penicillin acylase has a single-amino-acid catalytic centre
@en
Penicillin acylase has a single-amino-acid catalytic centre
@nl
type
label
Penicillin acylase has a single-amino-acid catalytic centre
@ast
Penicillin acylase has a single-amino-acid catalytic centre
@en
Penicillin acylase has a single-amino-acid catalytic centre
@nl
prefLabel
Penicillin acylase has a single-amino-acid catalytic centre
@ast
Penicillin acylase has a single-amino-acid catalytic centre
@en
Penicillin acylase has a single-amino-acid catalytic centre
@nl
P2093
P3181
P356
P1433
P1476
Penicillin acylase has a single-amino-acid catalytic centre
@en
P2093
P2888
P3181
P356
10.1038/373264A0
P407
P577
1995-01-19T00:00:00Z
P6179
1012679415