The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate
about
Trp-107 and trp-253 account for the increased steady state fluorescence that accompanies the conformational change in human pancreatic triglyceride lipase induced by tetrahydrolipstatin and bile saltThe x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxidesCrystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interestCrystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitorStructural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidaseConformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol LipaseLipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complexStructure and activity of rat pancreatic lipase-related protein 2Influence of a lipid interface on protein dynamics in a fungal lipase.Lipid lateral organization in fluid interfaces controls the rate of colipase associationVertebrate hepatic lipase genes and proteins: a review supported by bioinformatic studiesThe β5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2).Synthesis of 2-Oxo amide triacylglycerol analogues and study of their inhibition effect on pancreatic and gastric lipases.A proposed architecture for lecithin cholesterol acyl transferase (LCAT): identification of the catalytic triad and molecular modeling.S28 peptidases: lessons from a seemingly 'dysfunctional' family of two.A novel fluorogenic substrate for the measurement of endothelial lipase activity.Structure-Based Optimization and Biological Evaluation of Pancreatic Lipase Inhibitors as Novel Potential Antiobesity Agents.Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.Structural and functional properties of an unusual internal fusion peptide in a nonenveloped virus membrane fusion protein.Prediction and evaluation of the lipase inhibitory activities of tea polyphenols with 3D-QSAR modelsEffects of surfactants on lipase structure, activity, and inhibition.Probing structural transitions in both structured and disordered proteins using site-directed spin-labeling EPR spectroscopy.The role of seaweed bioactives in the control of digestion: implications for obesity treatments.Antilipase and antiproliferative activities of novel fluoroquinolones and triazolofluoroquinolones.Selection of orlistat as a potential inhibitor for lipase from Candida species.Regulation of lumen fat digestion: enzymic aspects.Crystal structure of cutinase covalently inhibited by a triglyceride analogueHigh-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitorsOpen and closed states of Candida antarctica lipase B: protonation and the mechanism of interfacial activation.Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family.Novel trifluoromethyl ketones as potent gastric lipase inhibitors.N-terminal peptide of Rhizopus oryzae lipase is important for its catalytic properties.The adsorption-desorption behaviour and structure function relationships of bile salts.Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).Identification of 1H-indene-(1,3,5,6)-tetrol derivatives as potent pancreatic lipase inhibitors using molecular docking and molecular dynamics approach.A mixed molecular modeling-robotics approach to investigate lipase large molecular motions.Evaluation of a novel thermo-alkaline Staphylococcus aureus lipase for application in detergent formulations.
P2860
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P2860
The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@ast
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@en
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@nl
type
label
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@ast
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@en
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@nl
prefLabel
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@ast
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@en
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@nl
P2093
P3181
P356
P1433
P1476
The 2.46 A resolution structur ...... ted by a C11 alkyl phosphonate
@en
P2093
C Cambillau
H van Tilbeurgh
M P Egloff
P304
P3181
P356
10.1021/BI00009A003
P407
P577
1995-03-07T00:00:00Z