Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)
about
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionInteractions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein familyCrystal structure of an RNA aptamer bound to thrombinVertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.Covalent ligation studies on the human telomere quadruplex.A novel method of screening thrombin-inhibiting DNA aptamers using an evolution-mimicking algorithm.Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activityCrystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid LigandStructural basis of DNA quadruplex-duplex junction formationPhotoresponsive Formation of an Intermolecular Minimal G-Quadruplex MotifSolution structure of the Na+ form of the dimeric guanine quadruplex [d(G3T4G3)]2An update on recent patents on thrombin inhibitors (2010 - 2013)Stability-activity relationships of a family of G-tetrad forming oligonucleotides as potent HIV inhibitors. A basis for anti-HIV drug designT30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1Finding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMRCharacterization of enhanced monovalent and bivalent thrombin DNA aptamer binding using single molecule force spectroscopy.Electrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex.Structural studies on LNA quadruplexes.Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanismG-quadruplex structure of an anti-proliferative DNA sequence.Structure in nascent RNA leads to termination of slippage transcription by T7 RNA polymerase.Structure of the biologically relevant G-quadruplex in the c-MYC promoter.Telomeric repeat-containing RNA structure in living cells.Quadruplex structures in nucleic acids.Biological aspects of DNA/RNA quadruplexes.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Beyond nucleic acid base pairs: from triads to heptads.Conformational changes in quadruplex oligonucleotide structures probed by Raman spectroscopyHuman telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.The contribution of thymine-thymine interactions to the stability of folded dimeric quadruplexesExplaining the varied glycosidic conformational, G-tract length and sequence preferences for anti-parallel G-quadruplexesKinetic partitioning modulates human telomere DNA G-quadruplex structural polymorphism.Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agentsd(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformationsMolecular beacon DNA probes and their bioanalytical applications.Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer.The role of thrombin exosites I and II in the activation of human coagulation factor V.Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis.Single-molecule investigation of G-quadruplex using a nanopore sensor.
P2860
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P2860
Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@ast
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@en
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@nl
type
label
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@ast
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@en
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@nl
prefLabel
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@ast
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@en
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@nl
P2093
P3181
P356
P1476
Three-dimensional solution str ...... DNA aptamer d(GGTTGGTGTGGTTGG)
@en
P2093
P304
P3181
P356
10.1006/JMBI.1994.1105
P577
1994-02-04T00:00:00Z