Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites
about
Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VIThe structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding siteThe crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolutionBiophysical characterization of refolded Drosophila Spätzle, a cystine knot protein, reveals distinct properties of three isoformsVascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding siteHigh resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptorsConformational plasticity of proNGFSingle cycle structure-based humanization of an anti-nerve growth factor therapeutic antibodyCrystallization of Spätzle, a cystine-knot protein involved in embryonic development and innate immunity in Drosophila melanogaster.Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 miceSimulated unbound structures for benchmarking of protein docking in the DOCKGROUND resourceThe structure of nerve growth factor in complex with lysophosphatidylinositol.Mutational studies of conserved residues in the dimer interface of nerve growth factorThe interaction of neurotrophins with the p75NTR common neurotrophin receptor: a comprehensive molecular modeling study.Two restricted sites on the surface of the nerve growth factor molecule independently determine specific TrkA receptor binding and activation.Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor.Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.Structural determinants of neurotrophin action.Neurotrophic factor changes in the rat thick skin following chronic constriction injury of the sciatic nerveThe role of the nerve growth factor carboxyl terminus in receptor binding and conformational stability.Novel anion-independent iron coordination by members of a third class of bacterial periplasmic ferric ion-binding proteins.The conundrum of the high-affinity NGF binding site formation unveiled?Role of the conformational versatility of the neurotrophin N-terminal regions in their recognition by Trk receptors.Nerve growth factor: structure/function relationships.Heterodimeric neurotrophins induce phosphorylation of Trk receptors and promote neuronal differentiation in PC12 cells.Zinc and Alzheimer's Disease: An Update.Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish.Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS.Solution Structure and Internal Motion of a Bioactive Peptide Derived from Nerve Growth Factor
P2860
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P2860
Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Nerve growth factor in differe ...... and reveals zinc binding sites
@ast
Nerve growth factor in differe ...... and reveals zinc binding sites
@en
Nerve growth factor in differe ...... and reveals zinc binding sites
@nl
type
label
Nerve growth factor in differe ...... and reveals zinc binding sites
@ast
Nerve growth factor in differe ...... and reveals zinc binding sites
@en
Nerve growth factor in differe ...... and reveals zinc binding sites
@nl
prefLabel
Nerve growth factor in differe ...... and reveals zinc binding sites
@ast
Nerve growth factor in differe ...... and reveals zinc binding sites
@en
Nerve growth factor in differe ...... and reveals zinc binding sites
@nl
P2093
P356
P1476
Nerve growth factor in differe ...... and reveals zinc binding sites
@en
P2093
B W Matthews
D R Holland
L S Cousens
P304
P356
10.1006/JMBI.1994.1380
P407
P577
1994-06-10T00:00:00Z