Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b
about
Allosteric inhibition of glycogen phosphorylaseaby the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarboxylateFR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylaseThe crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase.Structural and mechanistic insights into the bifunctional enzyme isocitrate dehydrogenase kinase/phosphatase AceK.Laue and monochromatic diffraction studies on catalysis in phosphorylase b crystals.Glycogen and its metabolism: some new developments and old themes.Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells.Mechanism of regulation in yeast glycogen phosphorylase.The structure of brain glycogen phosphorylase-from allosteric regulation mechanisms to clinical perspectives.Thermal denaturation pathway of starch phosphorylase from Corynebacterium callunae: oxyanion binding provides the glue that efficiently stabilizes the dimer structure of the proteinMechanism of thermal denaturation of maltodextrin phosphorylase from Escherichia coli.Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose.Surface induced dissociation yields quaternary substructure of refractory noncovalent phosphorylase B and glutamate dehydrogenase complexes.The regulation of glycogenolysis in the brain.Chimeric muscle and brain glycogen phosphorylases define protein domains governing isozyme-specific responses to allosteric activation.
P2860
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P2860
Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Crystallographic binding studi ...... state glycogen phosphorylase b
@ast
Crystallographic binding studi ...... state glycogen phosphorylase b
@en
Crystallographic binding studi ...... state glycogen phosphorylase b
@nl
type
label
Crystallographic binding studi ...... state glycogen phosphorylase b
@ast
Crystallographic binding studi ...... state glycogen phosphorylase b
@en
Crystallographic binding studi ...... state glycogen phosphorylase b
@nl
prefLabel
Crystallographic binding studi ...... state glycogen phosphorylase b
@ast
Crystallographic binding studi ...... state glycogen phosphorylase b
@en
Crystallographic binding studi ...... state glycogen phosphorylase b
@nl
P2093
P356
P1476
Crystallographic binding studi ...... state glycogen phosphorylase b
@en
P2093
Johnson LN
Oikonomakos NG
P304
P356
10.1006/JMBI.1993.1380
P577
1993-07-01T00:00:00Z