Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols
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Stretched exponential decay and correlations in the catalytic activity of fluctuating single lipase moleculesEnantioselectivity in Candida antarctica lipase B: a molecular dynamics studyA computational methodology to screen activities of enzyme variantsFunctional motions of Candida antarctica lipase B: a survey through open-close conformationsCrystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interestStructural Redesign of Lipase B from Candida antarctica by Circular Permutation and Incremental TruncationA model of the pressure dependence of the enantioselectivity of Candida rugosalipase towards (+/-)-mentholA unique mono- and diacylglycerol lipase from Penicillium cyclopium: heterologous expression, biochemical characterization and molecular basis for its substrate selectivityA general protein purification and immobilization method on controlled porosity glass: biocatalytic applicationsEnzymatic synthesis of alpha-butylglucoside lactate: a new alpha-hydroxy acid derivative.Modeling structure and flexibility of Candida antarctica lipase B in organic solvents.Structure-based substrate screening for an enzyme.Validating computer simulations of enantioselective catalysis; reproducing the large steric and entropic contributions in Candida Antarctica lipase BHow the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes.Analysis of the conformational stability and activity of Candida antarctica lipase B in organic solvents: insight from molecular dynamics and quantum mechanics/simulations.Crystallization and preliminary X-ray crystallographic studies of the N-terminal domain of human ribosomal protein L7a (RPL7a).Experimental lineage and functional analysis of a remotely directed peptide epoxidation catalyst.Kinetics of binding of fluorescent ligands to enzymes with engineered access tunnels.Interfacial Activation of Candida antarctica Lipase B: Combined Evidence from Experiment and Simulation.Gates of enzymes.The Lid Domain in Lipases: Structural and Functional Determinant of Enzymatic Properties.Adaptational properties and applications of cold-active lipases from psychrophilic bacteria.Enthalpic and entropic contributions in the transesterification of sucrose: computational study of lipases and subtilisin.Specificity in lipases: a computational study of transesterification of sucrose.Green polymer chemistry: enzyme catalysis for polymer functionalization.Geometric Simulation Approach for Grading and Assessing the Thermostability of CALBs.Acetylsalicylic acid (aspirin) reduces damage to reconstituted human tissues infected with Candida species by inhibiting extracellular fungal lipasesMolecular modeling of the enantioselectivity in lipase-catalyzed transesterification reactions.Crystal structure of cutinase covalently inhibited by a triglyceride analogueIn silico screening of 393 mutants facilitates enzyme engineering of amidase activity in CalB.Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases.Open and closed states of Candida antarctica lipase B: protonation and the mechanism of interfacial activation.Enantioselectivity of recombinant Rhizomucor miehei lipase in the ring opening of oxazolin-5(4H)-ones.A two-step enzymatic resolution process for large-scale production of (S)- and (R)-ethyl-3-hydroxybutyrate.Thermostabilization of Bacillus subtilis lipase A by minimizing the structural deformation caused by packing enhancement.The relationship between enhanced enzyme activity and structural dynamics in ionic liquids: a combined computational and experimental study.Is the ring conformation the most critical parameter in lipase-catalysed acylation of cycloalkanols?Creating space for large secondary alcohols by rational redesign of Candida antarctica lipase B.An inverse substrate orientation for the regioselective acylation of 3',5'-diaminonucleosides catalyzed by Candida antarctica lipase B?Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity.
P2860
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P2860
Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Crystallographic and molecular ...... pocket for secondary alcohols
@ast
Crystallographic and molecular ...... pocket for secondary alcohols
@en
Crystallographic and molecular ...... pocket for secondary alcohols
@nl
type
label
Crystallographic and molecular ...... pocket for secondary alcohols
@ast
Crystallographic and molecular ...... pocket for secondary alcohols
@en
Crystallographic and molecular ...... pocket for secondary alcohols
@nl
prefLabel
Crystallographic and molecular ...... pocket for secondary alcohols
@ast
Crystallographic and molecular ...... pocket for secondary alcohols
@en
Crystallographic and molecular ...... pocket for secondary alcohols
@nl
P2093
P3181
P356
P1433
P1476
Crystallographic and molecular ...... pocket for secondary alcohols
@en
P2093
J Uppenberg
T Anthonsen
P304
16838-16851
P3181
P356
10.1021/BI00051A035
P407
P577
1995-12-01T00:00:00Z