Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate
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Structural and functional diversity of the microbial kinomeMultiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1Structural and mechanistic insights into Mps1 kinase activationIn-plate protein crystallization, in situ ligand soaking and X-ray diffractionConservation, variability and the modeling of active protein kinasesCharacterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinaseDecoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein KinasesWNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain IIDeletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function.Structural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection.Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation.Yet another "active" pseudokinase, Erb3Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress.Unactivated PKR exists in an open conformation capable of binding nucleotidesMolecular determinants of substrate recognition in hematopoietic protein-tyrosine phosphatase.An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors.Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteinsJuvenile administration of concomitant methylphenidate and fluoxetine alters behavioral reactivity to reward- and mood-related stimuli and disrupts ventral tegmental area gene expression in adulthoodBMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs.Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.Extracellular signal-regulated kinase 2 signaling in the hippocampal dentate gyrus mediates the antidepressant effects of testosterone.Characterization of the Catalytic and Nucleotide Binding Properties of the α-Kinase Domain of Dictyostelium Myosin-II Heavy Chain Kinase AA CDK-related kinase regulates the length and assembly of flagella in Chlamydomonas.Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.Structure of extracellular signal-regulated kinase 2 in complex with ATP and ADP.Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylationErk1 and Erk2 are required for maintenance of hematopoietic stem cells and adult hematopoiesis.Ca(2+)/calmodulin-dependent protein kinases.How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study.Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactionsProfiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood.Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.It takes two to tango--signalling by dimeric Raf kinases.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.A pickup in pseudokinase activity.The CDK-activating kinase (Cak1p) from budding yeast has an unusual ATP-binding pocket.Nucleotide-binding mechanisms in pseudokinases.ERK mutations confer resistance to mitogen-activated protein kinase pathway inhibitors.Involvement of the mitogen-activated protein kinase SIMK in regulation of root hair tip growth
P2860
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P2860
Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@ast
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@en
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@nl
type
label
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@ast
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@en
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@nl
prefLabel
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@ast
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@en
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@nl
P2093
P356
P1433
P1476
Mutation of position 52 in ERK ...... for adenosine 5'-triphosphate
@en
P2093
E J Goldsmith
J W Haycock
M J Robinson
P C Harkins
P304
P356
10.1021/BI952723E
P407
P577
1996-05-07T00:00:00Z