Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP)
about
Evolution and horizontal transfer of dUTPase-encoding genes in viruses and their hosts3D domain swapping: as domains continue to swapKeeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPasesFlexible segments modulate co-folding of dUTPase and nucleocapsid proteinsStructure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15Tying down the arm in Bacillus dUTPase: structure and mechanismKinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzymeKinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania majorCatalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.The Methanococcus jannaschii dCTP deaminase is a bifunctional deaminase and diphosphatase.House cleaning, a part of good housekeeping.Archaeal dUTPase enhances PCR amplifications with archaeal DNA polymerases by preventing dUTP incorporation.Chlorella virus-encoded deoxyuridine triphosphatases exhibit different temperature optima.Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide.Catalytic and structural role of the metal ion in dUTP pyrophosphataseHuman adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes.Mutant adenovirus type 9 E4 ORF1 genes define three protein regions required for transformation of CREF cells.A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides.Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency."Hidden" dUTPase sequence in human immunodeficiency virus type 1 gp120African swine fever virus dUTPase is a highly specific enzyme required for efficient replication in swine macrophages.Biochemical and phylogenetic characterization of the dUTPase from the archaeal virus SIRV.Properties of Leishmania major dUTP nucleotidohydrolase, a distinct nucleotide-hydrolysing enzyme in kinetoplastids.Characterization of deoxyuridine 5'-triphosphate nucleotidohydrolase from Trypanosoma cruzi.Multidimensional NMR identifies the conformational shift essential for catalytic competence in the 60-kDa Drosophila melanogaster dUTPase trimer.Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.The C-terminus of dUTPase: observation on flexibility using NMR.A tradeoff between protein stability and conformational mobility in homotrimeric dUTPases.Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase.Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes.Transient kinetics of ligand binding and role of the C-terminus in the dUTPase from equine infectious anemia virus.Kinetic properties and stereospecificity of the monomeric dUTPase from herpes simplex virus type 1.dUTPase from the retrovirus equine infectious anemia virus: specificity, turnover and inhibition.A consensus sequence for a functional human endogenous retrovirus K (HERV-K) dUTPase.Kinetic characterization of dUTPase from Escherichia coli.
P2860
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P2860
Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP)
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@ast
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@en
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@nl
type
label
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@ast
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@en
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@nl
prefLabel
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@ast
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@en
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@nl
P2093
P2860
P356
P1476
Crystal structure of the Esche ...... th a substrate analogue (dUDP)
@en
P2093
L A Svensson
P2860
P356
10.1038/NSB0696-532
P577
1996-06-01T00:00:00Z