Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C
about
Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase CGeneral and Versatile Autoinhibition of PLC IsozymesAn autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activationStructural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like ProteinsPhospholipase C is involved in kinetochore function in Saccharomyces cerevisiaeStrike a pose: Gαq complexes at the membraneMicroelectrophoresis of a bilayer-coated silica bead in an optical trap: application to enzymology.Phospholipase C-gamma contains introns shared by src homology 2 domains in many unrelated proteins.Action of phosphatidylinositol-specific phospholipase Cgamma1 on soluble and micellar substrates. Separating effects on catalysis from modulation of the surface.Molecular mechanisms of phospholipase C β3 autoinhibition.Functional cooperation between the IP3 receptor and phospholipase C secures the high sensitivity to light of Drosophila photoreceptors in vivo.Phospholipase C-mediated suppression of dark noise enables single-photon detection in Drosophila photoreceptors.Crystallization, optimization and preliminary X-ray characterization of a metal-dependent PI-PLC from Streptomyces antibioticus.Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.Intrinsic Pleckstrin Homology (PH) Domain Motion in Phospholipase C-β Exposes a Gβγ Protein Binding Site.Structural insights into phospholipase C-β function.Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain.The correlation between multidomain enzymes and multiple activation mechanisms--the case of phospholipase Cβ and its membrane interactions.Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.Dynamic Response of the C2 Domain of Protein Kinase Cα to Ca2+ Binding.Computational active site analysis of molecular pathways to improve functional classification of enzymes.Activation of PLC-delta1 by Gi/o-coupled receptor agonists.GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents.Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.MARCKS and MARCKS-like proteins in development and regeneration.The structure of a calcium-dependent phosphoinositide-specific phospholipase C fromPseudomonassp. 62186, the first from a Gram-negative bacterium
P2860
Q27643498-2AC2A113-D9E2-423B-804D-8B6E0DDA57B6Q27651494-AE385112-2A27-490B-853A-7B0EBF9BD068Q27671596-78EBBCE2-8CF3-4070-B923-7AA441CF5511Q27679160-0EA00E97-4027-4890-BEB7-5F5CBFA89396Q27932398-C753CAB3-8123-4029-B137-C15BB684E7F7Q30356183-55922652-5DB9-4DC8-A674-1B829B068206Q30666289-5F7EF833-CCC9-42F0-9508-C414B4A6C776Q31146448-8E392C35-D1D8-43A9-8D29-1E1175745483Q31920638-255FF289-68D9-4CD7-AA20-2A51D2361870Q35019768-7F53C4C3-A270-46C5-9744-C9BBB387F47BQ35069728-4E65EFEA-2714-4C95-A917-38F6A53F0022Q35871160-FE5E386E-8BC6-4E0E-AB11-2EE37B2D76EAQ36448239-001EF8F9-4B1C-43FA-B6F4-E1D65264B04DQ36702204-69CD5382-24BA-42A1-980C-8E8885331F11Q36831338-A03B2A8D-4F28-4C69-83B0-93F1ECCF0AF0Q36843204-A84A3874-BD92-43EC-9CA9-F7AFCEC86886Q36987728-28894DD7-450B-47CC-B938-BE159B331270Q37193142-4D53E946-4CFA-47DD-94D9-EA679FC109EBQ37415681-93A200B9-161C-47EA-94AB-F76A887D32FDQ37929950-D4A9EA4A-B83C-464E-8836-AB452B322052Q38749071-E09B4333-6622-4D47-A090-6082D750712EQ42381526-D5C79EE3-22CB-44DC-BCD0-E3B154ED4A7EQ42643262-A910663C-13A7-41C6-A1EB-E9BF9957A2CBQ44906272-6B8B7318-11BE-4370-8A0F-39DE1C8C37DCQ47274809-49AE4C5A-DBE6-4CC6-B132-E9CD0CA6EED6Q47720805-EF7C47C1-1C20-45E2-8114-74EF71884FE5Q54978517-419B4A33-8C7A-4697-B60B-D1AF58D84066Q56895893-AD1D4DC9-25E2-42A4-A048-36AAB1685D27
P2860
Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Structural mapping of the cata ...... itide-specific phospholipase C
@ast
Structural mapping of the cata ...... itide-specific phospholipase C
@en
Structural mapping of the cata ...... itide-specific phospholipase C
@nl
type
label
Structural mapping of the cata ...... itide-specific phospholipase C
@ast
Structural mapping of the cata ...... itide-specific phospholipase C
@en
Structural mapping of the cata ...... itide-specific phospholipase C
@nl
prefLabel
Structural mapping of the cata ...... itide-specific phospholipase C
@ast
Structural mapping of the cata ...... itide-specific phospholipase C
@en
Structural mapping of the cata ...... itide-specific phospholipase C
@nl
P2093
P356
P1433
P1476
Structural mapping of the cata ...... itide-specific phospholipase C
@en
P2093
P304
P356
10.1021/BI962512P
P407
P577
1997-02-01T00:00:00Z