A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility
about
Evolution of CASK into a Mg2+-sensitive kinaseCrystal structure of a conformation-selective casein kinase-1 inhibitorHigh resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.Contribution of Non-catalytic Core Residues to Activity and Regulation in Protein Kinase AStructure of dystrophia myotonica protein kinaseComparative surface geometry of the protein kinase familyStructure of the Antibiotic Resistance Factor Spectinomycin Phosphotransferase from Legionella pneumophilaStructural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6′)-Ie-APH(2′′)-IaMolecular Features of Product Release for the PKA Catalytic CycleAtomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor KinasesDeciphering the Arginine-binding preferences at the substrate-binding groove of Ser/Thr kinases by computational surface mappingDecoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein KinasesResidue Geometry Networks: A Rigidity-Based Approach to the Amino Acid Network and Evolutionary Rate AnalysisA transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A.Design and synthesis of inositolphosphoglycan putative insulin mediators.Correlated mutation analysis on the catalytic domains of serine/threonine protein kinases.Co-conserved features associated with cis regulation of ErbB tyrosine kinases.Crystal structures of PRK1 in complex with the clinical compounds lestaurtinib and tofacitinib reveal ligand induced conformational changes.PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis.Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR.The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A.Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange.The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module.Conserved water molecules contribute to the extensive network of interactions at the active site of protein kinase APhosphoryl Transfer Reaction Snapshots in Crystals: INSIGHTS INTO THE MECHANISM OF PROTEIN KINASE A CATALYTIC SUBUNIT.Macrophage proliferation is regulated through CSF-1 receptor tyrosines 544, 559, and 807.Release of ADP from the catalytic subunit of protein kinase A: a molecular dynamics simulation study.Syk inhibits the activity of protein kinase A by phosphorylating tyrosine 330 of the catalytic subunitInfluence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A.GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail.Salt stress triggers phosphorylation of the Arabidopsis vacuolar K+ channel TPK1 by calcium-dependent protein kinases (CDPKs)A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1.600 ps molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase.Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.Electronic measurements of single-molecule catalysis by cAMP-dependent protein kinase A.Insights into nucleotide binding in protein kinase A using fluorescent adenosine derivatives.Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer.Kinase conformations: a computational study of the effect of ligand binding.Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase.
P2860
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P2860
A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A binary complex of the cataly ...... nes conformational flexibility
@ast
A binary complex of the cataly ...... nes conformational flexibility
@en
A binary complex of the cataly ...... nes conformational flexibility
@nl
type
label
A binary complex of the cataly ...... nes conformational flexibility
@ast
A binary complex of the cataly ...... nes conformational flexibility
@en
A binary complex of the cataly ...... nes conformational flexibility
@nl
prefLabel
A binary complex of the cataly ...... nes conformational flexibility
@ast
A binary complex of the cataly ...... nes conformational flexibility
@en
A binary complex of the cataly ...... nes conformational flexibility
@nl
P2093
P3181
P1433
P1476
A binary complex of the cataly ...... nes conformational flexibility
@en
P2093
L F Ten Eyck
N Narayana
S S Taylor
X Nguyen-huu
P304
P3181
P356
10.1016/S0969-2126(97)00246-3
P577
1997-07-15T00:00:00Z