Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis
about
Molecular and biochemical characterisation of a novel sulphatase gene: Arylsulfatase G (ARSG)Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationshipFunctional consequences of the subdomain organization of the sulfsBacterial Sphingomyelinases and Phospholipases as Virulence FactorsDefective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophyStructure of human estrone sulfatase suggests functional roles of membrane associationFunction and Structure of a Prokaryotic Formylglycine-generating EnzymeThe Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV AStructure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIARegulation of lysosomal ion homeostasis by channels and transportersA superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatasesMolecular genetics of mucopolysaccharidosis type IIIA and IIIB: Diagnostic, clinical, and biological implicationsDeveloping therapeutic approaches for metachromatic leukodystrophyIdentification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilageStructural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatasesComparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked geneOverview of protein structural and functional folds.Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate bindingConserved core structure and active site residues in alkaline phosphatase superfamily enzymes.Cloning of a mucin-desulfating sulfatase gene from Prevotella strain RS2 and its expression using a Bacteroides recombinant system.Molecular characterization of the human Calpha-formylglycine-generating enzyme.A new type of bacterial sulfatase reveals a novel maturation pathway in prokaryotes.Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivoInsights into Hunter syndrome from the structure of iduronate-2-sulfataseAmino acid residues forming the active site of arylsulfatase A. Role in catalytic activity and substrate binding.Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.High resolution crystal structure of human β-glucuronidase reveals structural basis of lysosome targeting.Structure and molecular mechanism of Bacillus anthracis cofactor-independent phosphoglycerate mutase: a crucial enzyme for spores and growing cells of Bacillus species.Matching the Diversity of Sulfated Biomolecules: Creation of a Classification Database for Sulfatases Reflecting Their Substrate Specificity.Lysophospholipid interactions with protein targets.A review of coumarin derivatives in pharmacotherapy of breast cancer.Glycosulfatase-Encoding Gene Cluster in Bifidobacterium breve UCC2003.Heparin/heparan sulfate 6-O-sulfatase from Flavobacterium heparinum: integrated structural and biochemical investigation of enzyme active site and substrate specificity.Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor.Sulfatase inhibitors: a patent review.Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer.Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. A structural and biochemical study of the enzyme active site and saccharide substrate specificity.Metachromatic Leukodystrophy (MLD): a Pakistani Family with Novel ARSA Gene Mutation.Site-selective incorporation and ligation of protein aldehydes.
P2860
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P2860
Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@ast
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@en
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@nl
type
label
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@ast
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@en
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@nl
prefLabel
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@ast
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@en
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@nl
P2093
P3181
P356
P1433
P1476
Crystal structure of human ary ...... m for sulfate ester hydrolysis
@en
P2093
P304
P3181
P356
10.1021/BI9714924
P407
P577
1998-03-01T00:00:00Z