The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
about
The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activitiesMolecular interactions of human Exo1 with DNAArginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationThe 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysisMolecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshiiDistant structural homology leads to the functional characterization of an archaeal PIN domain as an exonucleaseCrystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substratesCrystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operonCrystal structure of the Mus81-Eme1 complexStructural and biochemical studies of the 5′→3′ exoribonuclease Xrn1Structure of flap endonuclease 1 from the hyperthermophilic archaeonDesulfurococcus amylolyticusCoupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA DecayStructures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilyCrystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding AssemblyThe structure of Escherichia coli ExoIX--implications for DNA binding and catalysis in flap endonucleasesStructural basis of nuclear import of flap endonuclease 1 (FEN1)Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nucleaseCleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate.Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulationCalculating ensemble averaged descriptions of protein rigidity without samplingStructure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifsProliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stageMechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1Functional region prediction with a set of appropriate homologous sequences--an index for sequence selection by integrating structure and sequence information with spatial statistics.The protein components and mechanism of eukaryotic Okazaki fragment maturation.Molecular interactions of Escherichia coli ExoIX and identification of its associated 3'-5' exonuclease activity.Common fold in helix-hairpin-helix proteins.Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.Comprehensive classification of the PIN domain-like superfamilyUnusually wide co-factor tolerance in a metalloenzyme; divalent metal ions modulate endo-exonuclease activity in T5 exonuclease.Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavageBacteriophage T4 rnh (RNase H) null mutations: effects on spontaneous mutation and epistatic interaction with rII mutations.Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding.Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threadingThe Fen1 extrahelical 3'-flap pocket is conserved from archaea to human and regulates DNA substrate specificity.mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.
P2860
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P2860
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@ast
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@en
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@nl
type
label
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@ast
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@en
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@nl
prefLabel
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@ast
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@en
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@nl
P2093
P2860
P356
P1476
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii
@en
P2093
P2860
P304
P356
10.1038/1406
P577
1998-08-01T00:00:00Z