Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity
about
Coupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymesStructures of C3b in complex with factors B and D give insight into complement convertase formationPutting the structure into complementStructural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor DNew structural motifs on the chymotrypsin fold and their potential roles in complement factor BThe 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual featuresMechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217ASubstrate Modulation of Enzyme Activity in the Herpesvirus Protease FamilyStabilization of the E* Form Turns Thrombin into an AnticoagulantCrystal structure of prethrombin-1Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like ProteaseCrystal Structures of Prethrombin-2 Reveal Alternative Conformations under Identical Solution Conditions and the Mechanism of Zymogen ActivationThe structure of Human Microplasmin in Complex with Textilinin-1, an Aprotinin-like Inhibitor from the Australian Brown SnakeInhibiting Alternative Pathway Complement Activation by Targeting the Factor D ExositeExposure of R169 controls protein C activation and autoactivationEnsemble refinement shows conformational flexibility in crystal structures of human complement factor DEvidence of the E*-E equilibrium from rapid kinetics of Na+ binding to activated protein C and factor Xa.Allostery in trypsin-like proteases suggests new therapeutic strategies.Lutein Leads to a Decrease of Factor D Secretion by Cultured Mature Human Adipocytes.Conformational selection in trypsin-like proteases.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Serine proteases.C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.Production and functional activity of a recombinant von Willebrand factor-A domain from human complement factor B.Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
P2860
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P2860
Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Structures of native and compl ...... cific serine protease activity
@ast
Structures of native and compl ...... cific serine protease activity
@en
Structures of native and compl ...... cific serine protease activity
@nl
type
label
Structures of native and compl ...... cific serine protease activity
@ast
Structures of native and compl ...... cific serine protease activity
@en
Structures of native and compl ...... cific serine protease activity
@nl
prefLabel
Structures of native and compl ...... cific serine protease activity
@ast
Structures of native and compl ...... cific serine protease activity
@en
Structures of native and compl ...... cific serine protease activity
@nl
P2093
P356
P1476
Structures of native and compl ...... cific serine protease activity
@en
P2093
J E Volanakis
J M Kilpatrick
S V Narayana
P304
P356
10.1006/JMBI.1998.2089
P407
P577
1998-10-09T00:00:00Z